3iyp

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{{Seed}}
 
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[[Image:3iyp.jpg|left|200px]]
 
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==The Interaction of Decay-accelerating Factor with Echovirus 7==
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The line below this paragraph, containing "STRUCTURE_3iyp", creates the "Structure Box" on the page.
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<SX load='3iyp' size='340' side='right' viewer='molstar' caption='[[3iyp]], [[Resolution|resolution]] 7.20&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3iyp]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Echovirus_E7 Echovirus E7] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IYP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3IYP FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 7.2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DAO:LAURIC+ACID'>DAO</scene></td></tr>
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{{STRUCTURE_3iyp| PDB=3iyp | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3iyp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3iyp OCA], [https://pdbe.org/3iyp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3iyp RCSB], [https://www.ebi.ac.uk/pdbsum/3iyp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3iyp ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q91QV1_9ENTO Q91QV1_9ENTO]
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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Echovirus 7 (EV7) belongs to the enterovirus genus within the family Picornaviridae. Many picornaviruses use IgG-like receptors that bind into the viral canyon and are required to initiate viral uncoating during infection. However, in addition, some of the enteroviruses use an alternative or additional receptor that binds outside the canyon. Decay-accelerating factor (DAF) has been identified as a cellular receptor for EV7. The crystal structure of EV7 has been determined to 3.1 A resolution and used to interpret the 7.2 A resolution cryo-electron microscopy reconstruction of EV7 complexed with DAF. Each DAF binding site on EV7 is near a two-fold icosahedral symmetry axis, which differs from the binding site of DAF on the surface of coxsackievirus B3, indicating independent evolutionary processes by which DAF has been selected as a picornavirus accessory receptor. This suggests that there is an advantage for these viruses to recognize DAF during the initial process of infection.
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===The Interaction of Decay-accelerating Factor with Echovirus 7===
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The Interaction of Decay-accelerating Factor with Echovirus 7.,Plevka P, Hafenstein S, Harris KG, Cifuente JO, Zhang Y, Bowman VD, Chipman PR, Bator CM, Lin F, Medof ME, Rossmann MG J Virol. 2010 Sep 29. PMID:20881044<ref>PMID:20881044</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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<div class="pdbe-citations 3iyp" style="background-color:#fffaf0;"></div>
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==See Also==
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The line below this paragraph, {{ABSTRACT_PUBMED_20881044}}, adds the Publication Abstract to the page
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*[[CD55|CD55]]
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(as it appears on PubMed at http://www.pubmed.gov), where 20881044 is the PubMed ID number.
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*[[Virus coat proteins 3D structures|Virus coat proteins 3D structures]]
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== References ==
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{{ABSTRACT_PUBMED_20881044}}
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<references/>
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__TOC__
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==About this Structure==
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</SX>
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3IYP is a 5 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Human_echovirus_7 Human echovirus 7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IYP OCA].
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[[Category: Echovirus E7]]
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==Reference==
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<ref group="xtra">PMID:20881044</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Human echovirus 7]]
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[[Category: Large Structures]]
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[[Category: Bator, C M.]]
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[[Category: Bator CM]]
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[[Category: Bowman, V D.]]
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[[Category: Bowman VD]]
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[[Category: Chipman, P R.]]
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[[Category: Chipman PR]]
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[[Category: Ciefuente, J O.]]
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[[Category: Cifuente JO]]
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[[Category: Hafenstein, S.]]
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[[Category: Hafenstein S]]
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[[Category: Harris, K G.]]
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[[Category: Harris KG]]
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[[Category: Lin, F.]]
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[[Category: Lin F]]
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[[Category: Medof, D E.]]
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[[Category: Medof DE]]
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[[Category: Plevka, P.]]
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[[Category: Plevka P]]
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[[Category: Rossmann, M G.]]
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[[Category: Rossmann MG]]
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[[Category: Zhang, Y.]]
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[[Category: Zhang Y]]
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[[Category: Complex]]
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[[Category: Daf]]
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[[Category: Echovirus]]
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[[Category: Icosahedral virus]]
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[[Category: Receptor]]
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[[Category: Virus]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov 24 14:12:36 2010''
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Current revision

The Interaction of Decay-accelerating Factor with Echovirus 7

3iyp, resolution 7.20Å

Proteopedia Page Contributors and Editors (what is this?)

OCA

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