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3ar5
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 3ar5 is ON HOLD Authors: Toyoshima, C., Yonekura, S., Tsueda, J., Iwasawa, S. Description: Calcium pump crystal structure with bound TNP-AMP and TG...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Calcium pump crystal structure with bound TNP-AMP and TG== | |
| + | <StructureSection load='3ar5' size='340' side='right'caption='[[3ar5]], [[Resolution|resolution]] 2.20Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3ar5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AR5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3AR5 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PTY:PHOSPHATIDYLETHANOLAMINE'>PTY</scene>, <scene name='pdbligand=TG1:OCTANOIC+ACID+[3S-[3ALPHA,+3ABETA,+4ALPHA,+6BETA,+6ABETA,+7BETA,+8ALPHA(Z),+9BALPHA]]-6-(ACETYLOXY)-2,3,-3A,4,5,6,6A,7,8,9B-DECAHYDRO-3,3A-DIHYDROXY-3,6,9-TRIMETHYL-8-[(2-METHYL-1-OXO-2-BUTENYL)OX+Y]-2-OXO-4-(1-OXOBUTOXY)-AZULENO[4,5-B]FURAN-7-YL+ESTER'>TG1</scene>, <scene name='pdbligand=TM1:2,3-O-[(1R)-2,4,6-TRINITROCYCLOHEXA-2,5-DIENE-1,1-DIYL]ADENOSINE+5-(DIHYDROGEN+PHOSPHATE)'>TM1</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ar5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ar5 OCA], [https://pdbe.org/3ar5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ar5 RCSB], [https://www.ebi.ac.uk/pdbsum/3ar5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ar5 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/AT2A1_RABIT AT2A1_RABIT] This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen. Contributes to calcium sequestration involved in muscular excitation/contraction (By similarity). | ||
| - | + | ==See Also== | |
| - | + | *[[ATPase 3D structures|ATPase 3D structures]] | |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | [[Category: Large Structures]] | |
| + | [[Category: Oryctolagus cuniculus]] | ||
| + | [[Category: Iwasawa S]] | ||
| + | [[Category: Toyoshima C]] | ||
| + | [[Category: Tsueda J]] | ||
| + | [[Category: Yonekura S]] | ||
Current revision
Calcium pump crystal structure with bound TNP-AMP and TG
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