3pok
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 3pok is ON HOLD Authors: Barthelmes, K., Reynolds, A.M., Peisach, E., Jonker, H.R.A., DeNunzio, N.J., Allen, K.N., Imperiali, B., Schwalbe, H. Desc...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Interleukin-1-beta LBT L3 Mutant== | |
| + | <StructureSection load='3pok' size='340' side='right'caption='[[3pok]], [[Resolution|resolution]] 1.70Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3pok]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3POK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3POK FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7Å</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3pok FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pok OCA], [https://pdbe.org/3pok PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3pok RCSB], [https://www.ebi.ac.uk/pdbsum/3pok PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3pok ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/IL1B_HUMAN IL1B_HUMAN] Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.<ref>PMID:3920526</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Interleukin 3D structures|Interleukin 3D structures]] | |
| - | + | == References == | |
| - | + | <references/> | |
| - | + | __TOC__ | |
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Allen KN]] | ||
| + | [[Category: Barthelmes K]] | ||
| + | [[Category: DeNunzio NJ]] | ||
| + | [[Category: Imperiali B]] | ||
| + | [[Category: Jonker HRA]] | ||
| + | [[Category: Peisach E]] | ||
| + | [[Category: Reynolds AM]] | ||
| + | [[Category: Schwalbe H]] | ||
Current revision
Interleukin-1-beta LBT L3 Mutant
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