3pp2

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(New page: '''Unreleased structure''' The entry 3pp2 is ON HOLD Authors: Shen, L., Tempel, W., Tong, Y., Nedyalkova, L., Li, Y., Wernimont, A.K., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weig...)
Current revision (10:42, 21 February 2024) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 3pp2 is ON HOLD
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==Crystal structure of the pleckstrin homology domain of ArhGAP27==
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<StructureSection load='3pp2' size='340' side='right'caption='[[3pp2]], [[Resolution|resolution]] 1.42&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3pp2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PP2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PP2 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.421&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3pp2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pp2 OCA], [https://pdbe.org/3pp2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3pp2 RCSB], [https://www.ebi.ac.uk/pdbsum/3pp2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3pp2 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/RHG27_HUMAN RHG27_HUMAN] Rho GTPase-activating protein which may be involved in clathrin-mediated endocytosis. GTPase activators for the Rho-type GTPases act by converting them to an inactive GDP-bound state. Has activity toward CDC42 and RAC1 (By similarity).
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Authors: Shen, L., Tempel, W., Tong, Y., Nedyalkova, L., Li, Y., Wernimont, A.K., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Park, H., Structural Genomics Consortium (SGC)
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==See Also==
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*[[Rho GTPase activating protein 3D structures|Rho GTPase activating protein 3D structures]]
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Description: Crystal structure of the pleckstrin homology domain of ArhGAP27
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__TOC__
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</StructureSection>
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 1 11:15:00 2010''
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Arrowsmith CH]]
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[[Category: Bountra C]]
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[[Category: Edwards AM]]
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[[Category: Li Y]]
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[[Category: Nedyalkova L]]
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[[Category: Park H]]
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[[Category: Shen L]]
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[[Category: Tempel W]]
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[[Category: Tong Y]]
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[[Category: Weigelt J]]
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[[Category: Wernimont AK]]

Current revision

Crystal structure of the pleckstrin homology domain of ArhGAP27

PDB ID 3pp2

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