This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2e37

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
(New page: 200px<br /><applet load="2e37" size="350" color="white" frame="true" align="right" spinBox="true" caption="2e37, resolution 2.30&Aring;" /> '''Structure of TT0471 ...)
Current revision (17:20, 15 December 2021) (edit) (undo)
 
(15 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:2e37.jpg|left|200px]]<br /><applet load="2e37" size="350" color="white" frame="true" align="right" spinBox="true"
 
-
caption="2e37, resolution 2.30&Aring;" />
 
-
'''Structure of TT0471 protein from Thermus thermophilus'''<br />
 
-
==About this Structure==
+
==Structure of TT0471 protein from Thermus thermophilus==
-
2E37 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus] with <scene name='pdbligand=SO4:'>SO4</scene> and <scene name='pdbligand=NAD:'>NAD</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/L-lactate_dehydrogenase L-lactate dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.27 1.1.1.27] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E37 OCA].
+
<StructureSection load='2e37' size='340' side='right'caption='[[2e37]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
-
[[Category: L-lactate dehydrogenase]]
+
== Structural highlights ==
-
[[Category: Single protein]]
+
<table><tr><td colspan='2'>[[2e37]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Thet8 Thet8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E37 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2E37 FirstGlance]. <br>
-
[[Category: Thermus thermophilus]]
+
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-
[[Category: Lokanath, N.K.]]
+
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-
[[Category: RSGI, RIKEN.Structural.Genomics/Proteomics.Initiative.]]
+
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/L-lactate_dehydrogenase L-lactate dehydrogenase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.27 1.1.1.27] </span></td></tr>
-
[[Category: NAD]]
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2e37 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e37 OCA], [https://pdbe.org/2e37 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2e37 RCSB], [https://www.ebi.ac.uk/pdbsum/2e37 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2e37 ProSAT], [https://www.topsan.org/Proteins/RSGI/2e37 TOPSAN]</span></td></tr>
-
[[Category: SO4]]
+
</table>
-
[[Category: nad/nadp binding dehydrogenase]]
+
== Evolutionary Conservation ==
-
[[Category: national project on protein structural and functional analyses]]
+
[[Image:Consurf_key_small.gif|200px|right]]
-
[[Category: nppsfa]]
+
Check<jmol>
-
[[Category: oxidoreductase]]
+
<jmolCheckbox>
-
[[Category: riken structural genomics/proteomics initiative]]
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e3/2e37_consurf.spt"</scriptWhenChecked>
-
[[Category: rsgi]]
+
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-
[[Category: structural genomics]]
+
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2e37 ConSurf].
 +
<div style="clear:both"></div>
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 23 11:57:58 2008''
+
==See Also==
 +
*[[Lactate dehydrogenase 3D structures|Lactate dehydrogenase 3D structures]]
 +
__TOC__
 +
</StructureSection>
 +
[[Category: L-lactate dehydrogenase]]
 +
[[Category: Large Structures]]
 +
[[Category: Thet8]]
 +
[[Category: Lokanath, N K]]
 +
[[Category: Structural genomic]]
 +
[[Category: Nad/nadp binding dehydrogenase]]
 +
[[Category: National project on protein structural and functional analyse]]
 +
[[Category: Nppsfa]]
 +
[[Category: Oxidoreductase]]
 +
[[Category: Rsgi]]

Current revision

Structure of TT0471 protein from Thermus thermophilus

PDB ID 2e37

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools