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3otd
From Proteopedia
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| - | {{Seed}} | ||
| - | [[Image:3otd.png|left|200px]] | ||
| - | + | ==Crystal structure of human tRNAHis guanylyltransferase (Thg1)- NaI derivative== | |
| - | + | <StructureSection load='3otd' size='340' side='right'caption='[[3otd]], [[Resolution|resolution]] 2.28Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3otd]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OTD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3OTD FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.28Å</td></tr> | |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3otd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3otd OCA], [https://pdbe.org/3otd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3otd RCSB], [https://www.ebi.ac.uk/pdbsum/3otd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3otd ProSAT]</span></td></tr> | |
| - | + | </table> | |
| - | + | == Function == | |
| - | + | [https://www.uniprot.org/uniprot/THG1_HUMAN THG1_HUMAN] Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage. This step is essential for proper recognition of the tRNA and for the fidelity of protein synthesis.<ref>PMID:21059936</ref> | |
| - | + | == References == | |
| - | < | + | <references/> |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
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[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Doublie S]] |
| - | + | [[Category: Eckenroth BE]] | |
| - | [[Category: | + | [[Category: Hyde SJ]] |
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Current revision
Crystal structure of human tRNAHis guanylyltransferase (Thg1)- NaI derivative
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