3pr2
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 3pr2 is ON HOLD Authors: Lai, J., Niks, D., Wang, Y., Domratcheva, T., Barends, T.R.M., Schwarz, F., Olsen, R.A., Elliott, D.W., Fatmi, M.Q., Chang,...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Tryptophan synthase indoline quinonoid structure with F9 inhibitor in alpha site== | |
| + | <StructureSection load='3pr2' size='340' side='right'caption='[[3pr2]], [[Resolution|resolution]] 1.85Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3pr2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium Salmonella enterica subsp. enterica serovar Typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PR2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PR2 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=7MN:(Z)-N-[(1E)-1-CARBOXY-2-(2,3-DIHYDRO-1H-INDOL-1-YL)ETHYLIDENE]{3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4(1H)-YLIDENE}METHANAMINIUM'>7MN</scene>, <scene name='pdbligand=CS:CESIUM+ION'>CS</scene>, <scene name='pdbligand=F9F:2-({[4-(TRIFLUOROMETHOXY)PHENYL]SULFONYL}AMINO)ETHYL+DIHYDROGEN+PHOSPHATE'>F9F</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3pr2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pr2 OCA], [https://pdbe.org/3pr2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3pr2 RCSB], [https://www.ebi.ac.uk/pdbsum/3pr2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3pr2 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/TRPA_SALTY TRPA_SALTY] The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. | ||
| - | + | ==See Also== | |
| - | + | *[[Tryptophan synthase 3D structures|Tryptophan synthase 3D structures]] | |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | [[Category: Large Structures]] | |
| + | [[Category: Salmonella enterica subsp. enterica serovar Typhimurium]] | ||
| + | [[Category: Barends TRM]] | ||
| + | [[Category: Chang CA]] | ||
| + | [[Category: Domratcheva T]] | ||
| + | [[Category: Dunn MF]] | ||
| + | [[Category: Elliott DW]] | ||
| + | [[Category: Fatmi MQ]] | ||
| + | [[Category: Lai J]] | ||
| + | [[Category: Mueller LJ]] | ||
| + | [[Category: Niks D]] | ||
| + | [[Category: Olsen RA]] | ||
| + | [[Category: Schlichting I]] | ||
| + | [[Category: Schwarz F]] | ||
| + | [[Category: Wang Y]] | ||
Current revision
Tryptophan synthase indoline quinonoid structure with F9 inhibitor in alpha site
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