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3pso
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 3pso is ON HOLD Authors: Swarbrick, J, Shaw, D, Chhabra, S, Ghai, R, Valkov, E, Norwood, S, Seaman, M, Collins, B Description: Crystal structure of...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of mouse VPS29 complexed with Zn2+== | |
| + | <StructureSection load='3pso' size='340' side='right'caption='[[3pso]], [[Resolution|resolution]] 3.20Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3pso]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3lh6 3lh6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PSO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PSO FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3pso FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pso OCA], [https://pdbe.org/3pso PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3pso RCSB], [https://www.ebi.ac.uk/pdbsum/3pso PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3pso ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/VPS29_MOUSE VPS29_MOUSE] Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro) (By similarity). Has no activity towards p-nitrophenylphosphate, p-nitrophenylphosphorylcholine or phosphatidylinositlphosphates (in vitro). | ||
| - | + | ==See Also== | |
| - | + | *[[Vacuolar protein sorting-associated protein 3D structures|Vacuolar protein sorting-associated protein 3D structures]] | |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | [[Category: Large Structures]] | |
| + | [[Category: Mus musculus]] | ||
| + | [[Category: Chhabra S]] | ||
| + | [[Category: Collins B]] | ||
| + | [[Category: Ghai R]] | ||
| + | [[Category: Norwood S]] | ||
| + | [[Category: Shaw D]] | ||
| + | [[Category: Swarbrick J]] | ||
| + | [[Category: Valkov E]] | ||
Current revision
Crystal structure of mouse VPS29 complexed with Zn2+
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Categories: Large Structures | Mus musculus | Chhabra S | Collins B | Ghai R | Norwood S | Shaw D | Swarbrick J | Valkov E
