3fm8

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{{Seed}}
 
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[[Image:3fm8.png|left|200px]]
 
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==Crystal structure of full length centaurin alpha-1 bound with the FHA domain of KIF13B (CAPRI target)==
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The line below this paragraph, containing "STRUCTURE_3fm8", creates the "Structure Box" on the page.
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<StructureSection load='3fm8' size='340' side='right'caption='[[3fm8]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3fm8]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FM8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3FM8 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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{{STRUCTURE_3fm8| PDB=3fm8 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3fm8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fm8 OCA], [https://pdbe.org/3fm8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3fm8 RCSB], [https://www.ebi.ac.uk/pdbsum/3fm8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3fm8 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ADAP1_HUMAN ADAP1_HUMAN] GTPase-activating protein for the ADP ribosylation factor family (Probable). Binds phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and inositol 1,3,4,5-tetrakisphosphate (InsP4).<ref>PMID:10448098</ref> <ref>PMID:10333475</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fm/3fm8_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3fm8 ConSurf].
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<div style="clear:both"></div>
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===Crystal structure of full length centaurin alpha-1 bound with the FHA domain of KIF13B (CAPRI target)===
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==See Also==
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*[[Kinesin 3D Structures|Kinesin 3D Structures]]
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== References ==
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<references/>
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 21057110 is the PubMed ID number.
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</StructureSection>
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{{ABSTRACT_PUBMED_21057110}}
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==About this Structure==
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3FM8 is a 4 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FM8 OCA].
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==Reference==
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<ref group="xtra">PMID:21057110</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Arrowsmith, C H.]]
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[[Category: Large Structures]]
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[[Category: Bochkarev, A.]]
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[[Category: Arrowsmith CH]]
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[[Category: Bountra, C.]]
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[[Category: Bochkarev A]]
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[[Category: Edwards, A M.]]
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[[Category: Bountra C]]
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[[Category: MacKenzie, F.]]
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[[Category: Edwards AM]]
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[[Category: Park, H.]]
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[[Category: MacKenzie F]]
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[[Category: SGC, Structural Genomics Consortium.]]
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[[Category: Park H]]
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[[Category: Shen, L.]]
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[[Category: Shen L]]
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[[Category: Tempel, W.]]
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[[Category: Tempel W]]
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[[Category: Tong, Y.]]
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[[Category: Tong Y]]
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[[Category: Weigelt, J.]]
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[[Category: Weigelt J]]
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[[Category: Atp-binding]]
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[[Category: Cytoskeleton]]
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[[Category: Gap]]
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[[Category: Gtpase activation]]
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[[Category: Kinesin]]
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[[Category: Metal binding protein]]
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[[Category: Metal-binding]]
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[[Category: Microtubule]]
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[[Category: Motor protein]]
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[[Category: Nucleotide-binding]]
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[[Category: Nucleus]]
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[[Category: Phosphoprotein]]
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[[Category: Sgc]]
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[[Category: Structural genomics consortium]]
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[[Category: Transport protein-hydrolase activator complex]]
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[[Category: Zinc-finger]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 15 08:09:21 2010''
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Current revision

Crystal structure of full length centaurin alpha-1 bound with the FHA domain of KIF13B (CAPRI target)

PDB ID 3fm8

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