2jnt

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(New page: 200px<br /><applet load="2jnt" size="350" color="white" frame="true" align="right" spinBox="true" caption="2jnt" /> '''Structure of Bombyx mori Chemosensory Protei...)
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[[Image:2jnt.jpg|left|200px]]<br /><applet load="2jnt" size="350" color="white" frame="true" align="right" spinBox="true"
 
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caption="2jnt" />
 
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'''Structure of Bombyx mori Chemosensory Protein 1 in Solution'''<br />
 
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==Overview==
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==Structure of Bombyx mori Chemosensory Protein 1 in Solution==
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Chemosensory Proteins (CSPs) represent a family of conserved proteins, found in insects that may be involved in chemosensory functions. BmorCSP1, is expressed mainly in antennae and legs of the silkworm moth Bombyx mori, and was cloned from antennal cDNA. Here we report the determination of the, structure of Bombyx mori CSP1 (BmorCSP1) by NMR. The overall fold of, BmorCSP1 is globular and comprises six alpha-helices. These helices span, residues 10-14, 17-27, 35-49, 57-72, 75-85, and 92-100. The internal, hydrophobic sides of the helices are formed mostly by leucine and, isoleucine residues and, therefore, well suited to constitute a binding, site for hydrophobic ligands.
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<StructureSection load='2jnt' size='340' side='right'caption='[[2jnt]]' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2jnt]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bombyx_mori Bombyx mori]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JNT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JNT FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 10 models</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jnt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jnt OCA], [https://pdbe.org/2jnt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jnt RCSB], [https://www.ebi.ac.uk/pdbsum/2jnt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jnt ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q8MMK7_BOMMO Q8MMK7_BOMMO]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jn/2jnt_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2jnt ConSurf].
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<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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Chemosensory Proteins (CSPs) represent a family of conserved proteins found in insects that may be involved in chemosensory functions. BmorCSP1 is expressed mainly in antennae and legs of the silkworm moth Bombyx mori and was cloned from antennal cDNA. Here we report the determination of the structure of Bombyx mori CSP1 (BmorCSP1) by NMR. The overall fold of BmorCSP1 is globular and comprises six alpha-helices. These helices span residues 10-14, 17-27, 35-49, 57-72, 75-85, and 92-100. The internal hydrophobic sides of the helices are formed mostly by leucine and isoleucine residues and, therefore, well suited to constitute a binding site for hydrophobic ligands.
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==About this Structure==
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Structure of Bombyx mori chemosensory protein 1 in solution.,Jansen S, Chmelik J, Zidek L, Padrta P, Novak P, Zdrahal Z, Picimbon JF, Lofstedt C, Sklenar V Arch Insect Biochem Physiol. 2007 Nov;66(3):135-45. PMID:17966128<ref>PMID:17966128</ref>
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2JNT is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bombyx_mori Bombyx mori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JNT OCA].
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==Reference==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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Structure of Bombyx mori chemosensory protein 1 in solution., Jansen S, Chmelik J, Zidek L, Padrta P, Novak P, Zdrahal Z, Picimbon JF, Lofstedt C, Sklenar V, Arch Insect Biochem Physiol. 2007 Nov;66(3):135-45. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17966128 17966128]
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</div>
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<div class="pdbe-citations 2jnt" style="background-color:#fffaf0;"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
[[Category: Bombyx mori]]
[[Category: Bombyx mori]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Chmelik, J.]]
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[[Category: Chmelik J]]
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[[Category: Jansen, S.]]
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[[Category: Jansen S]]
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[[Category: Lofstedt, C.]]
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[[Category: Lofstedt C]]
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[[Category: Novak, P.]]
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[[Category: Novak P]]
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[[Category: Padrta, P.]]
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[[Category: Padrta P]]
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[[Category: Picimbon, J.]]
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[[Category: Picimbon J]]
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[[Category: Sklenar, V.]]
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[[Category: Sklenar V]]
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[[Category: Zidek, L.]]
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[[Category: Zidek L]]
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[[Category: bmorcsp1]]
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[[Category: csp1]]
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[[Category: ligand binding protein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 23 12:08:22 2008''
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Current revision

Structure of Bombyx mori Chemosensory Protein 1 in Solution

PDB ID 2jnt

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