3lz3

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{{Seed}}
 
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[[Image:3lz3.jpg|left|200px]]
 
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==Human aldose reductase mutant T113S complexed with IDD388==
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The line below this paragraph, containing "STRUCTURE_3lz3", creates the "Structure Box" on the page.
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<StructureSection load='3lz3' size='340' side='right'caption='[[3lz3]], [[Resolution|resolution]] 1.03&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3lz3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LZ3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3LZ3 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.03&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=388:(2-{[(4-BROMO-2-FLUOROBENZYL)AMINO]CARBONYL}-5-CHLOROPHENOXY)ACETIC+ACID'>388</scene>, <scene name='pdbligand=BR:BROMIDE+ION'>BR</scene>, <scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
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{{STRUCTURE_3lz3| PDB=3lz3 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3lz3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lz3 OCA], [https://pdbe.org/3lz3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3lz3 RCSB], [https://www.ebi.ac.uk/pdbsum/3lz3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3lz3 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ALDR_HUMAN ALDR_HUMAN] Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies.
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===Human aldose reductase mutant T113S complexed with IDD388===
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==See Also==
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*[[Aldose reductase 3D structures|Aldose reductase 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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3LZ3 is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LZ3 OCA].
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[[Category: Aldehyde reductase]]
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Heine, A.]]
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[[Category: Large Structures]]
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[[Category: Klebe, G.]]
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[[Category: Heine A]]
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[[Category: Koch, C.]]
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[[Category: Klebe G]]
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[[Category: Nadp]]
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[[Category: Koch C]]
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[[Category: Oxidoreductase]]
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[[Category: Oxidoreductase-oxidoreductase inhibitor complex]]
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[[Category: Phosphoprotein]]
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[[Category: T113s mutant]]
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[[Category: Tim barrel]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 15 08:41:36 2010''
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Current revision

Human aldose reductase mutant T113S complexed with IDD388

PDB ID 3lz3

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