3pz7

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(New page: '''Unreleased structure''' The entry 3pz7 is ON HOLD Authors: Liu, Y.T., Wang, J.W., Chen, L, Wu, J.W. Description: Molecular basis of WNT activation via the DIX-domain protein CCD1 '...)
Current revision (13:35, 1 March 2024) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 3pz7 is ON HOLD
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==Crystal structure of Ccd1-DIX domain==
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<StructureSection load='3pz7' size='340' side='right'caption='[[3pz7]], [[Resolution|resolution]] 2.44&Aring;' scene=''>
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Authors: Liu, Y.T., Wang, J.W., Chen, L, Wu, J.W.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3pz7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PZ7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PZ7 FirstGlance]. <br>
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Description: Molecular basis of WNT activation via the DIX-domain protein CCD1
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.441&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 22 09:38:28 2010''
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3pz7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pz7 OCA], [https://pdbe.org/3pz7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3pz7 RCSB], [https://www.ebi.ac.uk/pdbsum/3pz7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3pz7 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/DIXC1_HUMAN DIXC1_HUMAN] Positive effector of the Wnt signaling pathway; activates WNT3A signaling via DVL2. Regulates JNK activation by AXIN1 and DVL2.<ref>PMID:15262978</ref> <ref>PMID:21189423</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Chen L]]
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[[Category: Liu YT]]
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[[Category: Wang JW]]
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[[Category: Wu JW]]

Current revision

Crystal structure of Ccd1-DIX domain

PDB ID 3pz7

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