2x5i

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{{Seed}}
 
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[[Image:2x5i.jpg|left|200px]]
 
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==Crystal structure echovirus 7==
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The line below this paragraph, containing "STRUCTURE_2x5i", creates the "Structure Box" on the page.
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<StructureSection load='2x5i' size='340' side='right'caption='[[2x5i]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2x5i]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Echovirus_E7 Echovirus E7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X5I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2X5I FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.1&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DAO:LAURIC+ACID'>DAO</scene></td></tr>
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{{STRUCTURE_2x5i| PDB=2x5i | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2x5i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2x5i OCA], [https://pdbe.org/2x5i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2x5i RCSB], [https://www.ebi.ac.uk/pdbsum/2x5i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2x5i ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q6W9E5_9ENTO Q6W9E5_9ENTO]
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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Echovirus 7 (EV7) belongs to the enterovirus genus within the family Picornaviridae. Many picornaviruses use IgG-like receptors that bind into the viral canyon and are required to initiate viral uncoating during infection. However, in addition, some of the enteroviruses use an alternative or additional receptor that binds outside the canyon. Decay-accelerating factor (DAF) has been identified as a cellular receptor for EV7. The crystal structure of EV7 has been determined to 3.1 A resolution and used to interpret the 7.2 A resolution cryo-electron microscopy reconstruction of EV7 complexed with DAF. Each DAF binding site on EV7 is near a two-fold icosahedral symmetry axis, which differs from the binding site of DAF on the surface of coxsackievirus B3, indicating independent evolutionary processes by which DAF has been selected as a picornavirus accessory receptor. This suggests that there is an advantage for these viruses to recognize DAF during the initial process of infection.
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===CRYSTAL STRUCTURE ECHOVIRUS 7===
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The Interaction of Decay-accelerating Factor with Echovirus 7.,Plevka P, Hafenstein S, Harris KG, Cifuente JO, Zhang Y, Bowman VD, Chipman PR, Bator CM, Lin F, Medof ME, Rossmann MG J Virol. 2010 Sep 29. PMID:20881044<ref>PMID:20881044</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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<div class="pdbe-citations 2x5i" style="background-color:#fffaf0;"></div>
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==See Also==
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The line below this paragraph, {{ABSTRACT_PUBMED_20881044}}, adds the Publication Abstract to the page
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*[[Virus coat proteins 3D structures|Virus coat proteins 3D structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 20881044 is the PubMed ID number.
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== References ==
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<references/>
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{{ABSTRACT_PUBMED_20881044}}
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__TOC__
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</StructureSection>
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==About this Structure==
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[[Category: Echovirus E7]]
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2X5I is a 4 chains structure with sequences from [http://en.wikipedia.org/wiki/Human_echovirus_7 Human echovirus 7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X5I OCA].
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[[Category: Large Structures]]
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[[Category: Bator CM]]
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==Reference==
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[[Category: Bowman VD]]
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<ref group="xtra">PMID:20881044</ref><references group="xtra"/>
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[[Category: Chipman PR]]
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[[Category: Human echovirus 7]]
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[[Category: Hafenstein S]]
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[[Category: Bator, C M.]]
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[[Category: Plevka P]]
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[[Category: Bowman, V D.]]
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[[Category: Rossmann MG]]
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[[Category: Chipman, P R.]]
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[[Category: Zhang Y]]
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[[Category: Hafenstein, S.]]
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[[Category: Plevka, P.]]
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[[Category: Rossmann, M G.]]
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[[Category: Zhang, Y.]]
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[[Category: Capsid protein]]
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[[Category: Virus]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 22 09:49:59 2010''
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Current revision

Crystal structure echovirus 7

PDB ID 2x5i

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