Template:STRUCTURE 1dq8

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{{Structure
{{Structure
|PDB= {{{PDB}}}|SCENE={{{SCENE|}}}|SIZE={{{SIZE|350}}}|CAPTION={{{CAPTION|[[1dq8]], [[Resolution|resolution]] 2.10&Aring; (<scene name='initialview01'>default scene</scene>)}}}
|PDB= {{{PDB}}}|SCENE={{{SCENE|}}}|SIZE={{{SIZE|350}}}|CAPTION={{{CAPTION|[[1dq8]], [[Resolution|resolution]] 2.10&Aring; (<scene name='initialview01'>default scene</scene>)}}}
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|SITE= <scene name='pdbsite=AC1:Binding+Site+For+Residue+Coa+A+100'>AC1</scene>, <scene name='pdbsite=AC2:Binding+Site+For+Residue+Coa+B+101'>AC2</scene>, <scene name='pdbsite=AC3:Binding+Site+For+Residue+Coa+C+102'>AC3</scene>, <scene name='pdbsite=AC4:Binding+Site+For+Residue+Coa+D+103'>AC4</scene>, <scene name='pdbsite=AC5:Binding+Site+For+Residue+Mah+A+200'>AC5</scene>, <scene name='pdbsite=AC6:Binding+Site+For+Residue+Mah+B+201'>AC6</scene>, <scene name='pdbsite=AC7:Binding+Site+For+Residue+Mah+D+202'>AC7</scene>, <scene name='pdbsite=AC8:Binding+Site+For+Residue+Mah+D+203'>AC8</scene>, <scene name='pdbsite=AC9:Binding+Site+For+Residue+Dtt+C+301'>AC9</scene> and <scene name='pdbsite=BC1:Binding+Site+For+Residue+Dtt+B+302'>BC1</scene>
 
|LIGAND= <scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=DTT:2,3-DIHYDROXY-1,4-DITHIOBUTANE'>DTT</scene>, <scene name='pdbligand=MAH:3-HYDROXY-3-METHYL-GLUTARIC+ACID'>MAH</scene>
|LIGAND= <scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=DTT:2,3-DIHYDROXY-1,4-DITHIOBUTANE'>DTT</scene>, <scene name='pdbligand=MAH:3-HYDROXY-3-METHYL-GLUTARIC+ACID'>MAH</scene>
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Hydroxymethylglutaryl-CoA_reductase_(NADPH) Hydroxymethylglutaryl-CoA reductase (NADPH)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.34 1.1.1.34] </span>
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Hydroxymethylglutaryl-CoA_reductase_(NADPH) Hydroxymethylglutaryl-CoA reductase (NADPH)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.34 1.1.1.34] </span>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1dq8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dq8 OCA], [http://www.ebi.ac.uk/pdbsum/1dq8 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1dq8 RCSB]</span>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1dq8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dq8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1dq8 RCSB], [http://www.ebi.ac.uk/pdbsum/1dq8 PDBsum]</span>
|FUNCTION={{GO|id=GO:0016491 | text = oxidoreductase activity}}{{GO|id=GO:0004420 | text = hydroxymethylglutaryl-CoA reductase (NADPH) activity}}
|FUNCTION={{GO|id=GO:0016491 | text = oxidoreductase activity}}{{GO|id=GO:0004420 | text = hydroxymethylglutaryl-CoA reductase (NADPH) activity}}
|PROCESS={{GO|id=GO:0008354 | text = germ cell migration}}{{GO|id=GO:0006629 | text = lipid metabolic process}}{{GO|id=GO:0006695 | text = cholesterol biosynthetic process}}{{GO|id=GO:0008406 | text = gonad development}}{{GO|id=GO:0016126 | text = sterol biosynthetic process}}{{GO|id=GO:0008203 | text = cholesterol metabolic process}}{{GO|id=GO:0008610 | text = lipid biosynthetic process}}{{GO|id=GO:0009058 | text = biosynthetic process}}{{GO|id=GO:0006694 | text = steroid biosynthetic process}}
|PROCESS={{GO|id=GO:0008354 | text = germ cell migration}}{{GO|id=GO:0006629 | text = lipid metabolic process}}{{GO|id=GO:0006695 | text = cholesterol biosynthetic process}}{{GO|id=GO:0008406 | text = gonad development}}{{GO|id=GO:0016126 | text = sterol biosynthetic process}}{{GO|id=GO:0008203 | text = cholesterol metabolic process}}{{GO|id=GO:0008610 | text = lipid biosynthetic process}}{{GO|id=GO:0009058 | text = biosynthetic process}}{{GO|id=GO:0006694 | text = steroid biosynthetic process}}

Current revision

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1dq8, resolution 2.10Å ()
Ligands: , ,
Activity: Hydroxymethylglutaryl-CoA reductase (NADPH), with EC number 1.1.1.34
Resources: FirstGlance, OCA, RCSB, PDBsum
Coordinates: save as pdb, mmCIF, xml


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