This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2z1a

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
(New page: 200px<br /><applet load="2z1a" size="350" color="white" frame="true" align="right" spinBox="true" caption="2z1a, resolution 1.75&Aring;" /> '''Crystal structure of...)
Current revision (13:18, 1 November 2023) (edit) (undo)
 
(13 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:2z1a.jpg|left|200px]]<br /><applet load="2z1a" size="350" color="white" frame="true" align="right" spinBox="true"
 
-
caption="2z1a, resolution 1.75&Aring;" />
 
-
'''Crystal structure of 5'-nucleotidase precursor from Thermus thermophilus HB8'''<br />
 
-
==About this Structure==
+
==Crystal structure of 5'-nucleotidase precursor from Thermus thermophilus HB8==
-
2Z1A is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus] with <scene name='pdbligand=PO4:'>PO4</scene>, <scene name='pdbligand=ZN:'>ZN</scene> and <scene name='pdbligand=THM:'>THM</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/5'-nucleotidase 5'-nucleotidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.5 3.1.3.5] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z1A OCA].
+
<StructureSection load='2z1a' size='340' side='right'caption='[[2z1a]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
-
[[Category: 5'-nucleotidase]]
+
== Structural highlights ==
-
[[Category: Single protein]]
+
<table><tr><td colspan='2'>[[2z1a]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z1A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Z1A FirstGlance]. <br>
-
[[Category: Thermus thermophilus]]
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75&#8491;</td></tr>
-
[[Category: Kishishita, S.]]
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=THM:THYMIDINE'>THM</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-
[[Category: Kuramitsu, S.]]
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2z1a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z1a OCA], [https://pdbe.org/2z1a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2z1a RCSB], [https://www.ebi.ac.uk/pdbsum/2z1a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2z1a ProSAT], [https://www.topsan.org/Proteins/RSGI/2z1a TOPSAN]</span></td></tr>
-
[[Category: Nakagawa, N.]]
+
</table>
-
[[Category: RSGI, RIKEN.Structural.Genomics/Proteomics.Initiative.]]
+
== Function ==
-
[[Category: Yokoyama, S.]]
+
[https://www.uniprot.org/uniprot/Q5SIP1_THET8 Q5SIP1_THET8]
-
[[Category: PO4]]
+
== Evolutionary Conservation ==
-
[[Category: THM]]
+
[[Image:Consurf_key_small.gif|200px|right]]
-
[[Category: ZN]]
+
Check<jmol>
-
[[Category: hydrolase]]
+
<jmolCheckbox>
-
[[Category: metal-binding]]
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z1/2z1a_consurf.spt"</scriptWhenChecked>
-
[[Category: national project on protein structural and functional analyses]]
+
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-
[[Category: nppsfa]]
+
<text>to colour the structure by Evolutionary Conservation</text>
-
[[Category: nucleotidase]]
+
</jmolCheckbox>
-
[[Category: nucleotide-binding]]
+
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2z1a ConSurf].
-
[[Category: riken structural genomics/proteomics initiative]]
+
<div style="clear:both"></div>
-
[[Category: rsgi]]
+
__TOC__
-
[[Category: structural genomics]]
+
</StructureSection>
-
 
+
[[Category: Large Structures]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 23 12:17:32 2008''
+
[[Category: Thermus thermophilus HB8]]
 +
[[Category: Kishishita S]]
 +
[[Category: Kuramitsu S]]
 +
[[Category: Nakagawa N]]
 +
[[Category: Yokoyama S]]

Current revision

Crystal structure of 5'-nucleotidase precursor from Thermus thermophilus HB8

PDB ID 2z1a

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools