1mxe

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[[Image:1mxe.png|left|200px]]
 
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==Structure of the Complex of Calmodulin with the Target Sequence of CaMKI==
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The line below this paragraph, containing "STRUCTURE_1mxe", creates the "Structure Box" on the page.
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<StructureSection load='1mxe' size='340' side='right'caption='[[1mxe]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1mxe]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster] and [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MXE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MXE FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
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{{STRUCTURE_1mxe| PDB=1mxe | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mxe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mxe OCA], [https://pdbe.org/1mxe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mxe RCSB], [https://www.ebi.ac.uk/pdbsum/1mxe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mxe ProSAT]</span></td></tr>
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</table>
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===Structure of the Complex of Calmodulin with the Target Sequence of CaMKI===
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== Function ==
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[https://www.uniprot.org/uniprot/CALM_DROME CALM_DROME] Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 12475216 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mx/1mxe_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_12475216}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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[[1mxe]] is a 4 chain structure of [[Calmodulin]] with sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MXE OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1mxe ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Calmodulin]]
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*[[Calmodulin 3D structures|Calmodulin 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:12475216</ref><references group="xtra"/>
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[[Category: Calcium/calmodulin-dependent protein kinase]]
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[[Category: Drosophila melanogaster]]
[[Category: Drosophila melanogaster]]
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[[Category: Bayley, P M.]]
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[[Category: Large Structures]]
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[[Category: Clapperton, J A.]]
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[[Category: Rattus norvegicus]]
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[[Category: Gamblin, S J.]]
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[[Category: Bayley PM]]
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[[Category: Martin, S R.]]
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[[Category: Clapperton JA]]
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[[Category: Smerdon, S J.]]
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[[Category: Gamblin SJ]]
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[[Category: Calmodulin]]
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[[Category: Martin SR]]
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[[Category: Calmodulin-pepide complex]]
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[[Category: Smerdon SJ]]
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[[Category: Camki]]
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[[Category: Metal binding protein]]
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[[Category: Xray]]
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Current revision

Structure of the Complex of Calmodulin with the Target Sequence of CaMKI

PDB ID 1mxe

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