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3b7k

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(New page: 200px<br /><applet load="3b7k" size="350" color="white" frame="true" align="right" spinBox="true" caption="3b7k, resolution 2.70&Aring;" /> '''Human Acyl-coenzyme ...)
Current revision (12:03, 30 August 2023) (edit) (undo)
 
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[[Image:3b7k.gif|left|200px]]<br /><applet load="3b7k" size="350" color="white" frame="true" align="right" spinBox="true"
 
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caption="3b7k, resolution 2.70&Aring;" />
 
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'''Human Acyl-coenzyme A thioesterase 12'''<br />
 
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==About this Structure==
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==Human Acyl-coenzyme A thioesterase 12==
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3B7K is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=COA:'>COA</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Acetyl-CoA_hydrolase Acetyl-CoA hydrolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.2.1 3.1.2.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3B7K OCA].
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<StructureSection load='3b7k' size='340' side='right'caption='[[3b7k]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
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[[Category: Acetyl-CoA hydrolase]]
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== Structural highlights ==
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[[Category: Homo sapiens]]
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<table><tr><td colspan='2'>[[3b7k]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3B7K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3B7K FirstGlance]. <br>
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[[Category: Single protein]]
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
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[[Category: Arrowsmith, C.H.]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=COA:COENZYME+A'>COA</scene></td></tr>
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[[Category: Berg, S.Van.Den.]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3b7k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3b7k OCA], [https://pdbe.org/3b7k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3b7k RCSB], [https://www.ebi.ac.uk/pdbsum/3b7k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3b7k ProSAT]</span></td></tr>
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[[Category: Berglund, H.]]
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</table>
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[[Category: Busam, R.D.]]
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== Function ==
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[[Category: Collins, R.]]
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[https://www.uniprot.org/uniprot/ACO12_HUMAN ACO12_HUMAN] Hydrolyzes acetyl-CoA to acetate and CoA.<ref>PMID:16951743</ref>
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[[Category: Dahlgren, L.G.]]
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== Evolutionary Conservation ==
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[[Category: Edwards, A.M.]]
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[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Flodin, S.]]
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Check<jmol>
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[[Category: Flores, A.]]
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<jmolCheckbox>
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[[Category: Graslund, S.]]
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b7/3b7k_consurf.spt"</scriptWhenChecked>
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[[Category: Hallberg, B.M.]]
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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[[Category: Hammarstrom, M.]]
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<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: Herman, M.D.]]
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</jmolCheckbox>
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[[Category: Johansson, A.]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3b7k ConSurf].
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[[Category: Johansson, I.]]
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<div style="clear:both"></div>
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[[Category: Kallas, A.]]
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[[Category: Karlberg, T.]]
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[[Category: Kotenyova, T.]]
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[[Category: L., Svensson.]]
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[[Category: Lehtio, L.]]
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[[Category: Moche, M.]]
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[[Category: Nilsson, M.E.]]
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[[Category: Nordlund, P.]]
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[[Category: Nyman, T.]]
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[[Category: Persson, C.]]
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[[Category: SGC, Structural.Genomics.Consortium.]]
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[[Category: Sagemark, J.]]
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[[Category: Sundstrom, M.]]
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[[Category: Thorsell, A.G.]]
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[[Category: Tresaugues, L.]]
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[[Category: Weigelt, J.]]
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[[Category: Welin, M.]]
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[[Category: COA]]
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[[Category: cytoplasm]]
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[[Category: fatty acid metabolism]]
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[[Category: hotdog fold]]
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[[Category: hydrolase]]
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[[Category: lipid metabolism]]
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[[Category: serine esterase]]
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[[Category: sgc]]
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[[Category: structural genomics]]
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[[Category: structural genomics consortium]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 23 12:18:52 2008''
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==See Also==
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*[[Thioesterase 3D structures|Thioesterase 3D structures]]
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Arrowsmith CH]]
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[[Category: Berglund H]]
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[[Category: Busam RD]]
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[[Category: Collins R]]
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[[Category: Dahlgren LG]]
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[[Category: Edwards AM]]
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[[Category: Flodin S]]
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[[Category: Flores A]]
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[[Category: Graslund S]]
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[[Category: Hallberg BM]]
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[[Category: Hammarstrom M]]
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[[Category: Herman MD]]
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[[Category: Johansson A]]
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[[Category: Johansson I]]
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[[Category: Kallas A]]
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[[Category: Karlberg T]]
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[[Category: Kotenyova T]]
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[[Category: Lehtio L]]
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[[Category: Moche M]]
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[[Category: Nilsson ME]]
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[[Category: Nordlund P]]
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[[Category: Nyman T]]
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[[Category: Persson C]]
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[[Category: Sagemark J]]
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[[Category: Sundstrom M]]
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[[Category: Svensson L]]
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[[Category: Thorsell AG]]
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[[Category: Tresaugues L]]
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[[Category: Van Den Berg S]]
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[[Category: Weigelt J]]
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[[Category: Welin M]]

Current revision

Human Acyl-coenzyme A thioesterase 12

PDB ID 3b7k

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