1en4

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[[Image:1en4.png|left|200px]]
 
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==CRYSTAL STRUCTURE ANALYSIS OF THE E. COLI MANGANESE SUPEROXIDE DISMUTASE Q146H MUTANT==
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The line below this paragraph, containing "STRUCTURE_1en4", creates the "Structure Box" on the page.
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<StructureSection load='1en4' size='340' side='right'caption='[[1en4]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1en4]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EN4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1EN4 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
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{{STRUCTURE_1en4| PDB=1en4 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1en4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1en4 OCA], [https://pdbe.org/1en4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1en4 RCSB], [https://www.ebi.ac.uk/pdbsum/1en4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1en4 ProSAT]</span></td></tr>
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</table>
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===CRYSTAL STRUCTURE ANALYSIS OF THE E. COLI MANGANESE SUPEROXIDE DISMUTASE Q146H MUTANT===
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== Function ==
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[https://www.uniprot.org/uniprot/SODM_ECOLI SODM_ECOLI] Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 11141052 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/en/1en4_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_11141052}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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[[1en4]] is a 4 chain structure of [[Superoxide Dismutase]] with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EN4 OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1en4 ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Superoxide Dismutase]]
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*[[Superoxide dismutase 3D structures|Superoxide dismutase 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:11141052</ref><references group="xtra"/>
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Superoxide dismutase]]
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[[Category: Large Structures]]
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[[Category: Baker, E N.]]
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[[Category: Baker EN]]
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[[Category: Edwards, R A.]]
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[[Category: Edwards RA]]
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[[Category: Jameson, G B.]]
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[[Category: Jameson GB]]
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[[Category: Whittaker, J W.]]
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[[Category: Whittaker JW]]
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[[Category: Whittaker, M M.]]
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[[Category: Whittaker MM]]
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[[Category: Manganese superoxide dismutase]]
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[[Category: Mutant]]
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[[Category: Oxidoreductase]]
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[[Category: Proton shuttle]]
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[[Category: Q146h]]
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Current revision

CRYSTAL STRUCTURE ANALYSIS OF THE E. COLI MANGANESE SUPEROXIDE DISMUTASE Q146H MUTANT

PDB ID 1en4

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