1mkj
From Proteopedia
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- | [[Image:1mkj.png|left|200px]] | ||
- | + | ==Human Kinesin Motor Domain With Docked Neck Linker== | |
- | + | <StructureSection load='1mkj' size='340' side='right'caption='[[1mkj]], [[Resolution|resolution]] 2.70Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[1mkj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MKJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MKJ FirstGlance]. <br> | |
- | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7Å</td></tr> | |
- | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
- | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mkj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mkj OCA], [https://pdbe.org/1mkj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mkj RCSB], [https://www.ebi.ac.uk/pdbsum/1mkj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mkj ProSAT]</span></td></tr> | |
- | + | </table> | |
- | + | == Function == | |
- | + | [https://www.uniprot.org/uniprot/KINH_HUMAN KINH_HUMAN] Microtubule-dependent motor required for normal distribution of mitochondria and lysosomes (By similarity). | |
- | + | == Evolutionary Conservation == | |
- | < | + | [[Image:Consurf_key_small.gif|200px|right]] |
- | + | Check<jmol> | |
- | + | <jmolCheckbox> | |
- | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mk/1mkj_consurf.spt"</scriptWhenChecked> | |
- | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |
- | + | <text>to colour the structure by Evolutionary Conservation</text> | |
- | == | + | </jmolCheckbox> |
- | [[1mkj]] is a 1 chain structure | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1mkj ConSurf]. |
+ | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
- | *[[Kinesin]] | + | *[[Kinesin 3D Structures|Kinesin 3D Structures]] |
- | + | __TOC__ | |
- | + | </StructureSection> | |
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[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
- | [[Category: Budny | + | [[Category: Large Structures]] |
- | [[Category: Cooke | + | [[Category: Budny MJ]] |
- | [[Category: Fletterick | + | [[Category: Cooke R]] |
- | [[Category: Naber | + | [[Category: Fletterick R]] |
- | [[Category: Rice | + | [[Category: Naber N]] |
- | [[Category: Sindelar | + | [[Category: Rice S]] |
- | + | [[Category: Sindelar CV]] | |
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Current revision
Human Kinesin Motor Domain With Docked Neck Linker
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Categories: Homo sapiens | Large Structures | Budny MJ | Cooke R | Fletterick R | Naber N | Rice S | Sindelar CV