2cow

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[[Image:2cow.png|left|200px]]
 
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==Solution structure of the CAP-Gly domain in human Kinesin-like protein KIF13B==
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The line below this paragraph, containing "STRUCTURE_2cow", creates the "Structure Box" on the page.
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<StructureSection load='2cow' size='340' side='right'caption='[[2cow]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2cow]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2COW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2COW FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cow FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cow OCA], [https://pdbe.org/2cow PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cow RCSB], [https://www.ebi.ac.uk/pdbsum/2cow PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cow ProSAT], [https://www.topsan.org/Proteins/RSGI/2cow TOPSAN]</span></td></tr>
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{{STRUCTURE_2cow| PDB=2cow | SCENE= }}
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</table>
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== Function ==
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===Solution structure of the CAP-Gly domain in human Kinesin-like protein KIF13B===
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[https://www.uniprot.org/uniprot/KI13B_HUMAN KI13B_HUMAN] Involved in reorganization of the cortical cytoskeleton. Regulates axon formation by promoting the formation of extra axons. May be functionally important for the intracellular trafficking of MAGUKs and associated protein complexes.<ref>PMID:20194617</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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==About this Structure==
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Check<jmol>
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[[2cow]] is a 1 chain structure of [[Kinesin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2COW OCA].
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/co/2cow_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2cow ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Kinesin]]
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*[[Kinesin 3D Structures|Kinesin 3D Structures]]
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== References ==
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<references/>
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Inoue, M.]]
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[[Category: Large Structures]]
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[[Category: Kigawa, T.]]
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[[Category: Inoue M]]
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[[Category: Koshiba, S.]]
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[[Category: Kigawa T]]
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[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
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[[Category: Koshiba S]]
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[[Category: Saito, K.]]
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[[Category: Saito K]]
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[[Category: Yokoyama, S.]]
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[[Category: Yokoyama S]]
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[[Category: Cytoskeleton associated protein]]
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[[Category: Kiaa0639]]
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[[Category: Kinesin-like protein gakin]]
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[[Category: Microtubule binding]]
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[[Category: National project on protein structural and functional analyse]]
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[[Category: Nppsfa]]
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[[Category: Protein binding]]
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[[Category: Riken structural genomics/proteomics initiative]]
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[[Category: Rsgi]]
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[[Category: Structural genomic]]
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Current revision

Solution structure of the CAP-Gly domain in human Kinesin-like protein KIF13B

PDB ID 2cow

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Proteopedia Page Contributors and Editors (what is this?)

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