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1xp5

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[[Image:1xp5.png|left|200px]]
 
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==Structure Of The (Sr)Ca2+-ATPase E2-AlF4- Form==
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The line below this paragraph, containing "STRUCTURE_1xp5", creates the "Structure Box" on the page.
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<StructureSection load='1xp5' size='340' side='right'caption='[[1xp5]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1xp5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XP5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XP5 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ALF:TETRAFLUOROALUMINATE+ION'>ALF</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=TG1:OCTANOIC+ACID+[3S-[3ALPHA,+3ABETA,+4ALPHA,+6BETA,+6ABETA,+7BETA,+8ALPHA(Z),+9BALPHA]]-6-(ACETYLOXY)-2,3,-3A,4,5,6,6A,7,8,9B-DECAHYDRO-3,3A-DIHYDROXY-3,6,9-TRIMETHYL-8-[(2-METHYL-1-OXO-2-BUTENYL)OX+Y]-2-OXO-4-(1-OXOBUTOXY)-AZULENO[4,5-B]FURAN-7-YL+ESTER'>TG1</scene></td></tr>
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{{STRUCTURE_1xp5| PDB=1xp5 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xp5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xp5 OCA], [https://pdbe.org/1xp5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xp5 RCSB], [https://www.ebi.ac.uk/pdbsum/1xp5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xp5 ProSAT]</span></td></tr>
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</table>
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===Structure Of The (Sr)Ca2+-ATPase E2-AlF4- Form===
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== Function ==
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[https://www.uniprot.org/uniprot/AT2A1_RABIT AT2A1_RABIT] This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen. Contributes to calcium sequestration involved in muscular excitation/contraction (By similarity).
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== Evolutionary Conservation ==
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<!--
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_15618517}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 15618517 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xp/1xp5_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_15618517}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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[[1xp5]] is a 1 chain structure of [[ATPase]] with sequence from [http://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XP5 OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1xp5 ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[ATPase]]
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*[[ATPase 3D structures|ATPase 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:15618517</ref><references group="xtra"/>
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[[Category: Large Structures]]
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[[Category: Calcium-transporting ATPase]]
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[[Category: Oryctolagus cuniculus]]
[[Category: Oryctolagus cuniculus]]
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[[Category: Moller, J V.]]
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[[Category: Moller JV]]
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[[Category: Nielsen, R C.]]
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[[Category: Nielsen RC]]
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[[Category: Nissen, P.]]
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[[Category: Nissen P]]
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[[Category: Olesen, C.]]
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[[Category: Olesen C]]
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[[Category: Sorensen, T L.S.]]
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[[Category: Sorensen TLS]]
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[[Category: Aluminium fluoride]]
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[[Category: Ca2+-atpase]]
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[[Category: Hydrolase]]
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[[Category: Membrane protein]]
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[[Category: P-type atpase]]
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Current revision

Structure Of The (Sr)Ca2+-ATPase E2-AlF4- Form

PDB ID 1xp5

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