2q2l

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[[Image:2q2l.png|left|200px]]
 
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==Crystal Structure of Superoxide Dismutase from P. atrosanguina==
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The line below this paragraph, containing "STRUCTURE_2q2l", creates the "Structure Box" on the page.
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<StructureSection load='2q2l' size='340' side='right'caption='[[2q2l]], [[Resolution|resolution]] 2.37&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2q2l]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Potentilla_atrosanguinea Potentilla atrosanguinea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Q2L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Q2L FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.367&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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{{STRUCTURE_2q2l| PDB=2q2l | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2q2l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2q2l OCA], [https://pdbe.org/2q2l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2q2l RCSB], [https://www.ebi.ac.uk/pdbsum/2q2l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2q2l ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/B2CP37_9ROSA B2CP37_9ROSA] Destroys radicals which are normally produced within the cells and which are toxic to biological systems.[RuleBase:RU000393]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/q2/2q2l_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2q2l ConSurf].
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<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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Superoxide dismutase (SOD) from Potentilla atrosanguinea (Wall. ex. Lehm.) was crystallized using 20% PEG 3350 and 0.2 M ammonium iodide and diffraction data were collected to 2.36 A resolution using an in-house Cu Kalpha X-ray source. Analyses show that data with a redundancy of 3.2 were sufficient to determine the structure by the SAD technique using the iodine anomalous signal. This redundancy is lower than that in previous cases in which protein structures were determined using iodines for phasing and in-house copper X-ray sources. Cocrystallization of proteins with halide salts such as ammonium iodide in combination with copper-anode X-ray radiation can therefore serve as a powerful and easy avenue for structure solution.
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===Crystal Structure of Superoxide Dismutase from P. atrosanguina===
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SAD phasing of a structure based on cocrystallized iodides using an in-house Cu Kalpha X-ray source: effects of data redundancy and completeness on structure solution.,Yogavel M, Gill J, Mishra PC, Sharma A Acta Crystallogr D Biol Crystallogr. 2007 Aug;63(Pt 8):931-4. Epub 2007, Jul 17. PMID:17642520<ref>PMID:17642520</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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The line below this paragraph, {{ABSTRACT_PUBMED_17642520}}, adds the Publication Abstract to the page
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<div class="pdbe-citations 2q2l" style="background-color:#fffaf0;"></div>
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(as it appears on PubMed at http://www.pubmed.gov), where 17642520 is the PubMed ID number.
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{{ABSTRACT_PUBMED_17642520}}
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==About this Structure==
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[[2q2l]] is a 2 chain structure of [[Superoxide Dismutase]] with sequence from [http://en.wikipedia.org/wiki/Potentilla_atrosanguinea Potentilla atrosanguinea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Q2L OCA].
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==See Also==
==See Also==
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*[[Superoxide Dismutase]]
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*[[Superoxide dismutase 3D structures|Superoxide dismutase 3D structures]]
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:17642520</ref><references group="xtra"/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Potentilla atrosanguinea]]
[[Category: Potentilla atrosanguinea]]
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[[Category: Superoxide dismutase]]
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[[Category: Gill J]]
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[[Category: Gill, J.]]
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[[Category: Manickam Y]]
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[[Category: Manickam, Y.]]
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[[Category: Mishra PC]]
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[[Category: Mishra, P C.]]
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[[Category: Sharma A]]
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[[Category: Sharma, A.]]
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[[Category: Antioxidant]]
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[[Category: Metal-binding]]
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[[Category: Oxidoreductase]]
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[[Category: Sad]]
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[[Category: Sod]]
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Current revision

Crystal Structure of Superoxide Dismutase from P. atrosanguina

PDB ID 2q2l

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