This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
1xwj
From Proteopedia
(Difference between revisions)
m (Protected "1xwj" [edit=sysop:move=sysop]) |
|||
| (9 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | [[Image:1xwj.png|left|200px]] | ||
| - | + | ==Vinculin head (1-258) in complex with the talin vinculin binding site 3 (1945-1969)== | |
| - | + | <StructureSection load='1xwj' size='340' side='right'caption='[[1xwj]], [[Resolution|resolution]] 2.60Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[1xwj]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XWJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XWJ FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6Å</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xwj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xwj OCA], [https://pdbe.org/1xwj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xwj RCSB], [https://www.ebi.ac.uk/pdbsum/1xwj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xwj ProSAT]</span></td></tr> | |
| - | + | </table> | |
| - | + | == Function == | |
| - | + | [https://www.uniprot.org/uniprot/VINC_CHICK VINC_CHICK] Actin filament (F-actin)-binding protein involved in cell-matrix adhesion and cell-cell adhesion. Regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion.<ref>PMID:15229287</ref> <ref>PMID:20584916</ref> <ref>PMID:20086044</ref> | |
| - | + | == Evolutionary Conservation == | |
| - | + | [[Image:Consurf_key_small.gif|200px|right]] | |
| - | < | + | Check<jmol> |
| - | + | <jmolCheckbox> | |
| - | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xw/1xwj_consurf.spt"</scriptWhenChecked> | |
| - | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |
| - | + | <text>to colour the structure by Evolutionary Conservation</text> | |
| - | + | </jmolCheckbox> | |
| - | == | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1xwj ConSurf]. |
| - | [[1xwj]] is a 2 chain structure | + | <div style="clear:both"></div> |
==See Also== | ==See Also== | ||
| - | *[[Talin]] | + | *[[Talin 3D structures|Talin 3D structures]] |
| - | *[[Vinculin]] | + | *[[Vinculin|Vinculin]] |
| - | + | == References == | |
| - | == | + | <references/> |
| - | < | + | __TOC__ |
| + | </StructureSection> | ||
[[Category: Gallus gallus]] | [[Category: Gallus gallus]] | ||
| - | [[Category: Barsukov | + | [[Category: Large Structures]] |
| - | [[Category: Critchley | + | [[Category: Barsukov IL]] |
| - | [[Category: Emsley | + | [[Category: Critchley DR]] |
| - | [[Category: Gingras | + | [[Category: Emsley J]] |
| - | [[Category: Papagrigoriou | + | [[Category: Gingras AR]] |
| - | + | [[Category: Papagrigoriou E]] | |
| - | + | ||
| - | + | ||
Current revision
Vinculin head (1-258) in complex with the talin vinculin binding site 3 (1945-1969)
| |||||||||||
