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1y3g

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[[Image:1y3g.png|left|200px]]
 
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==Crystal Structure of a Silanediol Protease Inhibitor Bound to Thermolysin==
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The line below this paragraph, containing "STRUCTURE_1y3g", creates the "Structure Box" on the page.
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<StructureSection load='1y3g' size='340' side='right'caption='[[1y3g]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1y3g]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_thermoproteolyticus Bacillus thermoproteolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Y3G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Y3G FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3PL:3-PHENYLPROPANAL'>3PL</scene>, <scene name='pdbligand=AMM:(2S)-2-{[(AMINOMETHYL)(DIHYDROXY)SILYL]METHYL}-4-METHYLPENTANAL'>AMM</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=LEU:LEUCINE'>LEU</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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{{STRUCTURE_1y3g| PDB=1y3g | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1y3g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1y3g OCA], [https://pdbe.org/1y3g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1y3g RCSB], [https://www.ebi.ac.uk/pdbsum/1y3g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1y3g ProSAT]</span></td></tr>
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</table>
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===Crystal Structure of a Silanediol Protease Inhibitor Bound to Thermolysin===
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== Function ==
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[https://www.uniprot.org/uniprot/THER_BACTH THER_BACTH] Extracellular zinc metalloprotease.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 16342943 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/y3/1y3g_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_16342943}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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[[1y3g]] is a 1 chain structure of [[Thermolysin]] with sequence from [http://en.wikipedia.org/wiki/Bacillus_thermoproteolyticus Bacillus thermoproteolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Y3G OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1y3g ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Thermolysin]]
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*[[Thermolysin 3D structures|Thermolysin 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:16342943</ref><references group="xtra"/>
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[[Category: Bacillus thermoproteolyticus]]
[[Category: Bacillus thermoproteolyticus]]
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[[Category: Thermolysin]]
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[[Category: Large Structures]]
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[[Category: Juers, D H.]]
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[[Category: Juers DH]]
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[[Category: Kim, J.]]
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[[Category: Kim J]]
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[[Category: Matthews, B W.]]
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[[Category: Matthews BW]]
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[[Category: Sieburth, S M.]]
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[[Category: Sieburth SM]]
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[[Category: Hydrolase]]
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[[Category: Silanediol protease inhibitor]]
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[[Category: Thermolysin]]
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Current revision

Crystal Structure of a Silanediol Protease Inhibitor Bound to Thermolysin

PDB ID 1y3g

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