2aeo

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "2aeo" [edit=sysop:move=sysop])
Current revision (07:48, 30 October 2024) (edit) (undo)
 
(9 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:2aeo.png|left|200px]]
 
-
<!--
+
==Crystal structure of cisplatinated bovine Cu,Zn superoxide dismutase==
-
The line below this paragraph, containing "STRUCTURE_2aeo", creates the "Structure Box" on the page.
+
<StructureSection load='2aeo' size='340' side='right'caption='[[2aeo]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[2aeo]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AEO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2AEO FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CPT:CISPLATIN'>CPT</scene>, <scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-
{{STRUCTURE_2aeo| PDB=2aeo | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2aeo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2aeo OCA], [https://pdbe.org/2aeo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2aeo RCSB], [https://www.ebi.ac.uk/pdbsum/2aeo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2aeo ProSAT]</span></td></tr>
-
 
+
</table>
-
===Crystal structure of cisplatinated bovine Cu,Zn superoxide dismutase===
+
== Function ==
-
 
+
[https://www.uniprot.org/uniprot/SODC_BOVIN SODC_BOVIN] Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
-
 
+
== Evolutionary Conservation ==
-
==About this Structure==
+
[[Image:Consurf_key_small.gif|200px|right]]
-
[[2aeo]] is a 2 chain structure of [[Superoxide Dismutase]] with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AEO OCA].
+
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ae/2aeo_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2aeo ConSurf].
 +
<div style="clear:both"></div>
==See Also==
==See Also==
-
*[[Superoxide Dismutase]]
+
*[[Superoxide dismutase 3D structures|Superoxide dismutase 3D structures]]
-
 
+
__TOC__
-
==Reference==
+
</StructureSection>
-
<ref group="xtra">PMID:16416478</ref><ref group="xtra">PMID:11749487</ref><references group="xtra"/>
+
[[Category: Bos taurus]]
[[Category: Bos taurus]]
-
[[Category: Superoxide dismutase]]
+
[[Category: Large Structures]]
-
[[Category: Calderone, V.]]
+
[[Category: Calderone V]]
-
[[Category: Casini, A.]]
+
[[Category: Casini A]]
-
[[Category: Mangani, S.]]
+
[[Category: Mangani S]]
-
[[Category: Messori, L.]]
+
[[Category: Messori L]]
-
[[Category: Orioli, P L.]]
+
[[Category: Orioli PL]]
-
[[Category: Cancer]]
+
-
[[Category: Cisplatin]]
+
-
[[Category: Cu]]
+
-
[[Category: Metal based drug]]
+
-
[[Category: Oxidoreductase]]
+
-
[[Category: Platinum]]
+
-
[[Category: Protein]]
+
-
[[Category: Sod]]
+
-
[[Category: Zn sod]]
+

Current revision

Crystal structure of cisplatinated bovine Cu,Zn superoxide dismutase

PDB ID 2aeo

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools