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1wku
From Proteopedia
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| - | [[Image:1wku.png|left|200px]] | ||
| - | + | ==High resolution structure of the human alpha-actinin isoform 3== | |
| - | + | <StructureSection load='1wku' size='340' side='right'caption='[[1wku]], [[Resolution|resolution]] 1.60Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[1wku]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WKU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WKU FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6Å</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wku FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wku OCA], [https://pdbe.org/1wku PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wku RCSB], [https://www.ebi.ac.uk/pdbsum/1wku PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wku ProSAT]</span></td></tr> | |
| - | + | </table> | |
| - | + | == Function == | |
| - | + | [https://www.uniprot.org/uniprot/ACTN3_HUMAN ACTN3_HUMAN] F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein. | |
| - | + | == Evolutionary Conservation == | |
| - | + | [[Image:Consurf_key_small.gif|200px|right]] | |
| - | < | + | Check<jmol> |
| - | + | <jmolCheckbox> | |
| - | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wk/1wku_consurf.spt"</scriptWhenChecked> | |
| - | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |
| - | + | <text>to colour the structure by Evolutionary Conservation</text> | |
| - | + | </jmolCheckbox> | |
| - | == | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1wku ConSurf]. |
| - | [[1wku]] is a 2 chain structure | + | <div style="clear:both"></div> |
==See Also== | ==See Also== | ||
| - | *[[Actinin]] | + | *[[Actinin 3D structures|Actinin 3D structures]] |
| - | + | *[[Parvin|Parvin]] | |
| - | + | __TOC__ | |
| - | < | + | </StructureSection> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Carugo | + | [[Category: Large Structures]] |
| - | [[Category: Franzot | + | [[Category: Djinovic Carugo K]] |
| - | [[Category: Gautel | + | [[Category: Franzot G]] |
| - | [[Category: Sjoblom | + | [[Category: Gautel M]] |
| - | + | [[Category: Sjoblom B]] | |
| - | + | ||
| - | + | ||
Current revision
High resolution structure of the human alpha-actinin isoform 3
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