1pn7

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[[Image:1pn7.png|left|200px]]
 
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==Coordinates of S12, L11 proteins and P-tRNA, from the 70S X-ray structure aligned to the 70S Cryo-EM map of E.coli ribosome==
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The line below this paragraph, containing "STRUCTURE_1pn7", creates the "Structure Box" on the page.
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<SX load='1pn7' size='340' side='right' viewer='molstar' caption='[[1pn7]], [[Resolution|resolution]] 10.80&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1pn7]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima] and [https://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PN7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1PN7 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 10.8&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1pn7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1pn7 OCA], [https://pdbe.org/1pn7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1pn7 RCSB], [https://www.ebi.ac.uk/pdbsum/1pn7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1pn7 ProSAT]</span></td></tr>
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{{STRUCTURE_1pn7| PDB=1pn7 | SCENE= }}
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</table>
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== Function ==
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===Coordinates of S12, L11 proteins and P-tRNA, from the 70S X-ray structure aligned to the 70S Cryo-EM map of E.coli ribosome===
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[https://www.uniprot.org/uniprot/RS12_THET8 RS12_THET8] With S4 and S5 plays an important role in translational accuracy (By similarity).[HAMAP-Rule:MF_00403_B] Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.[HAMAP-Rule:MF_00403_B]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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(as it appears on PubMed at http://www.pubmed.gov), where 12859903 is the PubMed ID number.
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pn/1pn7_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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{{ABSTRACT_PUBMED_12859903}}
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==About this Structure==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1pn7 ConSurf].
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[[1pn7]] is a 3 chain structure of [[Ribosomal protein S12]] with sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima] and [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PN7 OCA].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Ribosomal protein S12]]
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*[[Ribosomal protein L11 3D structures|Ribosomal protein L11 3D structures]]
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*[[Ribosomal protein S12|Ribosomal protein S12]]
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==Reference==
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*[[Transfer RNA (tRNA)|Transfer RNA (tRNA)]]
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<ref group="xtra">PMID:12859903</ref><references group="xtra"/>
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__TOC__
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</SX>
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[[Category: Large Structures]]
[[Category: Thermotoga maritima]]
[[Category: Thermotoga maritima]]
[[Category: Thermus thermophilus]]
[[Category: Thermus thermophilus]]
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[[Category: Ehrenberg, M.]]
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[[Category: Ehrenberg M]]
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[[Category: Frank, J.]]
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[[Category: Frank J]]
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[[Category: Rawat, U.]]
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[[Category: Rawat U]]
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[[Category: Sengupta, J.]]
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[[Category: Sengupta J]]
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[[Category: Valle, M.]]
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[[Category: Valle M]]
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[[Category: Zavialov, A.]]
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[[Category: Zavialov A]]
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[[Category: Ribosomal protein]]
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[[Category: Rna binding protein/rna complex]]
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[[Category: Trna]]
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[[Category: Trna binding protein]]
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Current revision

Coordinates of S12, L11 proteins and P-tRNA, from the 70S X-ray structure aligned to the 70S Cryo-EM map of E.coli ribosome

1pn7, resolution 10.80Å

Proteopedia Page Contributors and Editors (what is this?)

OCA

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