2qdq

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[[Image:2qdq.png|left|200px]]
 
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==Crystal structure of the talin dimerisation domain==
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The line below this paragraph, containing "STRUCTURE_2qdq", creates the "Structure Box" on the page.
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<StructureSection load='2qdq' size='340' side='right'caption='[[2qdq]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2qdq]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QDQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QDQ FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qdq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qdq OCA], [https://pdbe.org/2qdq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qdq RCSB], [https://www.ebi.ac.uk/pdbsum/2qdq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qdq ProSAT]</span></td></tr>
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{{STRUCTURE_2qdq| PDB=2qdq | SCENE= }}
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</table>
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== Function ==
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===Crystal structure of the talin dimerisation domain===
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[https://www.uniprot.org/uniprot/TLN1_MOUSE TLN1_MOUSE] Probably involved in connections of major cytoskeletal structures to the plasma membrane. High molecular weight cytoskeletal protein concentrated at regions of cell-substratum contact and, in lymphocytes, at cell-cell contacts.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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(as it appears on PubMed at http://www.pubmed.gov), where 18157087 is the PubMed ID number.
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qd/2qdq_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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{{ABSTRACT_PUBMED_18157087}}
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==About this Structure==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2qdq ConSurf].
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[[2qdq]] is a 2 chain structure of [[Talin]] with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QDQ OCA].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Talin]]
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*[[Talin 3D structures|Talin 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:18157087</ref><references group="xtra"/>
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[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Barsukov, I L.]]
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[[Category: Barsukov IL]]
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[[Category: Bate, N.]]
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[[Category: Bate N]]
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[[Category: Critchley, D R.C.]]
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[[Category: Critchley DRC]]
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[[Category: Gingras, A R.]]
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[[Category: Gingras AR]]
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[[Category: Putz, N S.M.]]
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[[Category: Putz NSM]]
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[[Category: Abs3]]
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[[Category: C-terminal actin binding site]]
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[[Category: Dimerisation domain]]
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[[Category: Latch domain]]
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[[Category: Structural protein]]
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[[Category: Talin]]
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Current revision

Crystal structure of the talin dimerisation domain

PDB ID 2qdq

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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