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1to5
From Proteopedia
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| - | [[Image:1to5.png|left|200px]] | ||
| - | + | ==Structure of the cytosolic Cu,Zn SOD from S. mansoni== | |
| - | + | <StructureSection load='1to5' size='340' side='right'caption='[[1to5]], [[Resolution|resolution]] 2.20Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[1to5]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Schistosoma_mansoni Schistosoma mansoni]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TO5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1TO5 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr> | |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1to5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1to5 OCA], [https://pdbe.org/1to5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1to5 RCSB], [https://www.ebi.ac.uk/pdbsum/1to5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1to5 ProSAT]</span></td></tr> | |
| - | + | </table> | |
| - | + | == Function == | |
| - | + | [https://www.uniprot.org/uniprot/SODC_SCHMA SODC_SCHMA] Destroys radicals which are normally produced within the cells and which are toxic to biological systems. | |
| - | + | == Evolutionary Conservation == | |
| - | < | + | [[Image:Consurf_key_small.gif|200px|right]] |
| - | + | Check<jmol> | |
| - | + | <jmolCheckbox> | |
| - | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/to/1to5_consurf.spt"</scriptWhenChecked> | |
| - | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |
| - | + | <text>to colour the structure by Evolutionary Conservation</text> | |
| - | == | + | </jmolCheckbox> |
| - | [[1to5]] is a 4 chain structure | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1to5 ConSurf]. |
| + | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
| - | *[[Superoxide | + | *[[Superoxide dismutase 3D structures|Superoxide dismutase 3D structures]] |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | < | + | [[Category: Large Structures]] |
[[Category: Schistosoma mansoni]] | [[Category: Schistosoma mansoni]] | ||
| - | + | [[Category: Cardoso RMF]] | |
| - | + | [[Category: Garratt RC]] | |
| - | [[Category: Cardoso | + | [[Category: Silva CHTP]] |
| - | [[Category: Garratt | + | [[Category: Tanaka M]] |
| - | [[Category: Silva | + | [[Category: Tanaka T]] |
| - | [[Category: Tanaka | + | [[Category: Ulian de Araujo AP]] |
| - | [[Category: Tanaka | + | |
| - | [[Category: | + | |
| - | + | ||
Current revision
Structure of the cytosolic Cu,Zn SOD from S. mansoni
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