2hhh

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "2hhh" [edit=sysop:move=sysop])
Current revision (09:32, 14 February 2024) (edit) (undo)
 
(9 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:2hhh.png|left|200px]]
 
-
<!--
+
==Crystal structure of kasugamycin bound to the 30S ribosomal subunit==
-
The line below this paragraph, containing "STRUCTURE_2hhh", creates the "Structure Box" on the page.
+
<StructureSection load='2hhh' size='340' side='right'caption='[[2hhh]], [[Resolution|resolution]] 3.35&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[2hhh]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HHH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2HHH FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.35&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=KSG:(1S,2R,3S,4R,5S,6S)-2,3,4,5,6-PENTAHYDROXYCYCLOHEXYL+2-AMINO-4-{[CARBOXY(IMINO)METHYL]AMINO}-2,3,4,6-TETRADEOXY-ALPHA-D-ARABINO-HEXOPYRANOSIDE'>KSG</scene></td></tr>
-
{{STRUCTURE_2hhh| PDB=2hhh | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2hhh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hhh OCA], [https://pdbe.org/2hhh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2hhh RCSB], [https://www.ebi.ac.uk/pdbsum/2hhh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2hhh ProSAT], [https://www.topsan.org/Proteins/RSGI/2hhh TOPSAN]</span></td></tr>
-
 
+
</table>
-
===Crystal structure of kasugamycin bound to the 30S ribosomal subunit===
+
== Function ==
-
 
+
[https://www.uniprot.org/uniprot/RS2_THET8 RS2_THET8] Spans the head-body hinge region of the 30S subunit. Is loosely associated with the 30S subunit.[HAMAP-Rule:MF_00291_B]
-
 
+
== Evolutionary Conservation ==
-
<!--
+
[[Image:Consurf_key_small.gif|200px|right]]
-
The line below this paragraph, {{ABSTRACT_PUBMED_16998488}}, adds the Publication Abstract to the page
+
Check<jmol>
-
(as it appears on PubMed at http://www.pubmed.gov), where 16998488 is the PubMed ID number.
+
<jmolCheckbox>
-
-->
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hh/2hhh_consurf.spt"</scriptWhenChecked>
-
{{ABSTRACT_PUBMED_16998488}}
+
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-
 
+
<text>to colour the structure by Evolutionary Conservation</text>
-
==About this Structure==
+
</jmolCheckbox>
-
[[2hhh]] is a 21 chain structure of [[Ribosomal protein S10]], [[Ribosomal protein S11]], [[Ribosomal protein S12]], [[Ribosomal protein S13]], [[Ribosomal protein S15]], [[Ribosomal protein S17]], [[Ribosomal protein S2]], [[Ribosomal protein S20]], [[Ribosomal protein S3]], [[Ribosomal protein S4]] and [[Ribosomal protein THX]] with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus_hb8 Thermus thermophilus hb8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HHH OCA].
+
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2hhh ConSurf].
 +
<div style="clear:both"></div>
==See Also==
==See Also==
-
*[[Ribosomal protein S10]]
+
*[[Ribosomal protein THX 3D structures|Ribosomal protein THX 3D structures]]
-
*[[Ribosomal protein S11]]
+
*[[Ribosome 3D structures|Ribosome 3D structures]]
-
*[[Ribosomal protein S12]]
+
__TOC__
-
*[[Ribosomal protein S13]]
+
</StructureSection>
-
*[[Ribosomal protein S15]]
+
[[Category: Large Structures]]
-
*[[Ribosomal protein S17]]
+
[[Category: Thermus thermophilus HB8]]
-
*[[Ribosomal protein S2]]
+
[[Category: Schluenzen F]]
-
*[[Ribosomal protein S20]]
+
-
*[[Ribosomal protein S3]]
+
-
*[[Ribosomal protein S4]]
+
-
*[[Ribosomal protein THX]]
+
-
 
+
-
==Reference==
+
-
<ref group="xtra">PMID:16998488</ref><references group="xtra"/>
+
-
[[Category: Thermus thermophilus hb8]]
+
-
[[Category: Schluenzen, F.]]
+
-
[[Category: 30]]
+
-
[[Category: Antibiotic]]
+
-
[[Category: Initiation]]
+
-
[[Category: Ribosome]]
+

Current revision

Crystal structure of kasugamycin bound to the 30S ribosomal subunit

PDB ID 2hhh

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools