1xyv

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[[Image:1xyv.png|left|200px]]
 
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==Low Temperature (100K) Crystal Structure Of Flavodoxin Mutant S64C, monomer, semiquinone state==
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The line below this paragraph, containing "STRUCTURE_1xyv", creates the "Structure Box" on the page.
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<StructureSection load='1xyv' size='340' side='right'caption='[[1xyv]], [[Resolution|resolution]] 1.79&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1xyv]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Desulfovibrio_vulgaris Desulfovibrio vulgaris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XYV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XYV FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.79&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene></td></tr>
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{{STRUCTURE_1xyv| PDB=1xyv | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xyv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xyv OCA], [https://pdbe.org/1xyv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xyv RCSB], [https://www.ebi.ac.uk/pdbsum/1xyv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xyv ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/FLAV_DESVH FLAV_DESVH] Low-potential electron donor to a number of redox enzymes.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xy/1xyv_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1xyv ConSurf].
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<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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The mutant S64C of the short-chain flavodoxin from Desulfovibrio vulgaris has been designed to introduce an accessible and reactive group on the protein surface. Crystals have been obtained of both the monomeric and homodimeric forms of the protein, with the cofactor FMN in either the oxidized or the one electron-reduced (semiquinone) state, and the structures have been determined to high resolution. The redox properties of the different species have been investigated and the variations observed with respect to wild type have been related to the structural changes induced by the mutation and S-S bridge formation.
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===Low Temperature (100K) Crystal Structure Of Flavodoxin Mutant S64C, monomer, semiquinone state===
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Redox properties and crystal structures of a Desulfovibrio vulgaris flavodoxin mutant in the monomeric and homodimeric forms.,Fantuzzi A, Artali R, Bombieri G, Marchini N, Meneghetti F, Gilardi G, Sadeghi SJ, Cavazzini D, Rossi GL Biochim Biophys Acta. 2009 Mar;1794(3):496-505. Epub 2008 Dec 11. PMID:19118653<ref>PMID:19118653</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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The line below this paragraph, {{ABSTRACT_PUBMED_19118653}}, adds the Publication Abstract to the page
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<div class="pdbe-citations 1xyv" style="background-color:#fffaf0;"></div>
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(as it appears on PubMed at http://www.pubmed.gov), where 19118653 is the PubMed ID number.
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-->
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{{ABSTRACT_PUBMED_19118653}}
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==About this Structure==
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[[1xyv]] is a 1 chain structure of [[Flavodoxin]] with sequence from [http://en.wikipedia.org/wiki/Desulfovibrio_vulgaris Desulfovibrio vulgaris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XYV OCA].
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==See Also==
==See Also==
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*[[Flavodoxin]]
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*[[Flavodoxin 3D structures|Flavodoxin 3D structures]]
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:19118653</ref><references group="xtra"/>
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__TOC__
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</StructureSection>
[[Category: Desulfovibrio vulgaris]]
[[Category: Desulfovibrio vulgaris]]
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[[Category: Artali, R.]]
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[[Category: Large Structures]]
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[[Category: Bombieri, G.]]
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[[Category: Artali R]]
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[[Category: Cavazzini, D.]]
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[[Category: Bombieri G]]
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[[Category: Gilardi, G.]]
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[[Category: Cavazzini D]]
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[[Category: Marchini, N.]]
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[[Category: Gilardi G]]
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[[Category: Meneghetti, F.]]
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[[Category: Marchini N]]
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[[Category: Rossi, G L.]]
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[[Category: Meneghetti F]]
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[[Category: Electron transport]]
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[[Category: Rossi GL]]
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[[Category: Engineered]]
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[[Category: Flavodoxin]]
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[[Category: S64c mutant]]
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Current revision

Low Temperature (100K) Crystal Structure Of Flavodoxin Mutant S64C, monomer, semiquinone state

PDB ID 1xyv

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