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1n5r

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[[Image:1n5r.png|left|200px]]
 
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==Crystal structure of the mouse acetylcholinesterase-propidium complex==
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The line below this paragraph, containing "STRUCTURE_1n5r", creates the "Structure Box" on the page.
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<StructureSection load='1n5r' size='340' side='right'caption='[[1n5r]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1n5r]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N5R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1N5R FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.25&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=P6G:HEXAETHYLENE+GLYCOL'>P6G</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=PRM:3,8-DIAMINO-5[3-(DIETHYLMETHYLAMMONIO)PROPYL]-6-PHENYLPHENANTHRIDINIUM'>PRM</scene></td></tr>
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{{STRUCTURE_1n5r| PDB=1n5r | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1n5r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1n5r OCA], [https://pdbe.org/1n5r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1n5r RCSB], [https://www.ebi.ac.uk/pdbsum/1n5r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1n5r ProSAT]</span></td></tr>
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</table>
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===Crystal structure of the mouse acetylcholinesterase-propidium complex===
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== Function ==
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[https://www.uniprot.org/uniprot/ACES_MOUSE ACES_MOUSE] Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_12505979}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 12505979 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/n5/1n5r_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_12505979}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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[[1n5r]] is a 2 chain structure of [[Acetylcholinesterase]] with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N5R OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1n5r ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Acetylcholinesterase]]
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*[[Acetylcholinesterase 3D structures|Acetylcholinesterase 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:12505979</ref><references group="xtra"/>
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[[Category: Large Structures]]
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[[Category: Acetylcholinesterase]]
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[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Bourne, Y.]]
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[[Category: Bourne Y]]
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[[Category: Marchot, P.]]
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[[Category: Marchot P]]
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[[Category: Radic, Z.]]
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[[Category: Radic Z]]
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[[Category: Taylor, P.]]
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[[Category: Taylor P]]
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[[Category: Acetylcholinesterase]]
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[[Category: Glycosylated protein]]
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[[Category: Homodimer]]
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[[Category: Hydrolase]]
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[[Category: Hydrolase fold]]
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[[Category: Serine esterase]]
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Current revision

Crystal structure of the mouse acetylcholinesterase-propidium complex

PDB ID 1n5r

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