1mr6

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[[Image:1mr6.png|left|200px]]
 
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==Solution Structure of gamma-Bungarotoxin:Implication for the role of the Residues Adjacent to RGD in Integrin Binding==
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The line below this paragraph, containing "STRUCTURE_1mr6", creates the "Structure Box" on the page.
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<StructureSection load='1mr6' size='340' side='right'caption='[[1mr6]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1mr6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bungarus_multicinctus Bungarus multicinctus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MR6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MR6 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mr6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mr6 OCA], [https://pdbe.org/1mr6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mr6 RCSB], [https://www.ebi.ac.uk/pdbsum/1mr6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mr6 ProSAT]</span></td></tr>
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{{STRUCTURE_1mr6| PDB=1mr6 | SCENE= }}
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</table>
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== Function ==
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===Solution Structure of gamma-Bungarotoxin:Implication for the role of the Residues Adjacent to RGD in Integrin Binding===
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[https://www.uniprot.org/uniprot/3NO5I_BUNMU 3NO5I_BUNMU] Exhibits M2 muscarinic acetylcholine receptor (CHRM2)-blocking activity, but has a weak binding activity toward nicotinic AChR. Moreover, it inhibits collagen-induced platelet aggregation.<ref>PMID:12168693</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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(as it appears on PubMed at http://www.pubmed.gov), where 15390258 is the PubMed ID number.
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mr/1mr6_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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{{ABSTRACT_PUBMED_15390258}}
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==About this Structure==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1mr6 ConSurf].
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[[1mr6]] is a 1 chain structure of [[Bungarotoxin]] with sequence from [http://en.wikipedia.org/wiki/Bungarus_multicinctus Bungarus multicinctus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MR6 OCA].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Bungarotoxin]]
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*[[Bungarotoxin 3D structures|Bungarotoxin 3D structures]]
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:15390258</ref><references group="xtra"/>
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__TOC__
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</StructureSection>
[[Category: Bungarus multicinctus]]
[[Category: Bungarus multicinctus]]
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[[Category: Chang, L S.]]
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[[Category: Large Structures]]
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[[Category: Chen, C Y.]]
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[[Category: Chang L-S]]
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[[Category: Chen, Y C.]]
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[[Category: Chen C-Y]]
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[[Category: Chuang, W J.]]
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[[Category: Chen Y-C]]
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[[Category: Shiu, J H.]]
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[[Category: Chuang W-J]]
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[[Category: Neurotoxin]]
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[[Category: Shiu J-H]]
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[[Category: Venom]]
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Current revision

Solution Structure of gamma-Bungarotoxin:Implication for the role of the Residues Adjacent to RGD in Integrin Binding

PDB ID 1mr6

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