1jdo

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[[Image:1jdo.png|left|200px]]
 
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==SPERM WHALE MYOGLOBIN (FERROUS, NITRIC OXIDE BOUND)==
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The line below this paragraph, containing "STRUCTURE_1jdo", creates the "Structure Box" on the page.
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<StructureSection load='1jdo' size='340' side='right'caption='[[1jdo]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1jdo]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Physeter_catodon Physeter catodon]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JDO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JDO FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=NO:NITRIC+OXIDE'>NO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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{{STRUCTURE_1jdo| PDB=1jdo | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1jdo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jdo OCA], [https://pdbe.org/1jdo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1jdo RCSB], [https://www.ebi.ac.uk/pdbsum/1jdo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1jdo ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/MYG_PHYMC MYG_PHYMC] Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jd/1jdo_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1jdo ConSurf].
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<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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The structure of the ferrous nitric oxide form of native sperm whale myoglobin has been determined by X-ray crystallography to 1.7 angstroms resolution. The nitric oxide ligand is bent with respect to the heme plane: the Fe-N-O angle is 112 degrees. This angle is smaller than those observed in model compounds and in lupin leghemoglobin. The exact angle appears to be influenced by the strength of the proximal bond and hydrogen bonding interactions between the distal histidine and the bound ligand. Specifically, the N(epsilon) atom of histidine64 is located 2.8 angstroms away from the nitrogen atom of the bound ligand, implying electrostatic stabilization of the FeNO complex. This interpretation is supported by mutagenesis studies. When histidine64 is replaced with apolar amino acids, the rate of nitric oxide dissociation from myoglobin increases tenfold.
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===SPERM WHALE MYOGLOBIN (FERROUS, NITRIC OXIDE BOUND)===
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Nitric oxide myoglobin: crystal structure and analysis of ligand geometry.,Brucker EA, Olson JS, Ikeda-Saito M, Phillips GN Jr Proteins. 1998 Mar 1;30(4):352-6. PMID:9533619<ref>PMID:9533619</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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The line below this paragraph, {{ABSTRACT_PUBMED_9533619}}, adds the Publication Abstract to the page
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<div class="pdbe-citations 1jdo" style="background-color:#fffaf0;"></div>
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(as it appears on PubMed at http://www.pubmed.gov), where 9533619 is the PubMed ID number.
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{{ABSTRACT_PUBMED_9533619}}
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==About this Structure==
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[[1jdo]] is a 1 chain structure of [[Myoglobin]] with sequence from [http://en.wikipedia.org/wiki/Physeter_catodon Physeter catodon]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JDO OCA].
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==See Also==
==See Also==
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*[[Myoglobin]]
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*[[Myoglobin 3D structures|Myoglobin 3D structures]]
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:9533619</ref><references group="xtra"/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Physeter catodon]]
[[Category: Physeter catodon]]
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[[Category: Brucker, E A.]]
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[[Category: Brucker EA]]
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[[Category: Phillips, G N.]]
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[[Category: Phillips Jr GN]]
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[[Category: Globin]]
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[[Category: Heme]]
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[[Category: Nitric oxide]]
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[[Category: Oxygen storage]]
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[[Category: Oxygen transport]]
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Current revision

SPERM WHALE MYOGLOBIN (FERROUS, NITRIC OXIDE BOUND)

PDB ID 1jdo

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