1rgv

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "1rgv" [edit=sysop:move=sysop])
Current revision (06:04, 23 August 2023) (edit) (undo)
 
(9 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:1rgv.png|left|200px]]
 
-
<!--
+
==Crystal Structure of the Ferredoxin from Thauera aromatica==
-
The line below this paragraph, containing "STRUCTURE_1rgv", creates the "Structure Box" on the page.
+
<StructureSection load='1rgv' size='340' side='right'caption='[[1rgv]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[1rgv]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thauera_aromatica_K172 Thauera aromatica K172]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RGV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1RGV FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene></td></tr>
-
{{STRUCTURE_1rgv| PDB=1rgv | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1rgv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rgv OCA], [https://pdbe.org/1rgv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1rgv RCSB], [https://www.ebi.ac.uk/pdbsum/1rgv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1rgv ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/O88151_THAAR O88151_THAAR]
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rg/1rgv_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1rgv ConSurf].
 +
<div style="clear:both"></div>
 +
<div style="background-color:#fffaf0;">
 +
== Publication Abstract from PubMed ==
 +
4-Hydroxybenzoyl-CoA reductase (4-HBCR) is a central enzyme in the metabolism of phenolic compounds in anaerobic bacteria. The enzyme catalyzes the reductive removal of the phenolic hydroxyl group from 4-hydroxybenzoyl-CoA, yielding benzoyl-CoA and water. 4-HBCR belongs to the xanthine oxidase (XO) family of molybdenum enzymes which occur as heterodimers, (alphabetagamma)(2). 4-HBCR contains two molybdopterins, four [2Fe-2S] and two [4Fe-4S] clusters and two FADs. A low-potential Allochromatium vinosum-type ferredoxin containing two [4Fe-4S] clusters serves as an in vivo electron donor for 4-HBCR. In this work, the oxygen-sensitive proteins 4-HBCR and the ferredoxin (TaFd) from Thauera aromatica were crystallized under anaerobic conditions. 4-HBCR crystallized with PEG 4000 and MPD as precipitant diffracted to about 1.6 A resolution and the crystals were highly suitable for X-ray structure analysis. Crystals of TaFd were obtained with (NH(4))(3)PO(4) as precipitant and revealed a solvent content of 77%, which is remarkably high for a small soluble protein. The structure of TaFd was solved at 2.9 A resolution by the molecular-replacement method using the highly related structure of the ferredoxin (CvFd) from A. vinosum as a model. Structural changes between the two ferredoxins around the [4Fe-4S] cluster can be correlated with their different redox potentials.
-
===Crystal Structure of the Ferredoxin from Thauera aromatica===
+
Crystallization of 4-hydroxybenzoyl-CoA reductase and the structure of its electron donor ferredoxin.,Unciuleac M, Boll M, Warkentin E, Ermler U Acta Crystallogr D Biol Crystallogr. 2004 Feb;60(Pt 2):388-91. Epub 2004, Jan 23. PMID:14747735<ref>PMID:14747735</ref>
-
 
+
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
-
<!--
+
</div>
-
The line below this paragraph, {{ABSTRACT_PUBMED_14747735}}, adds the Publication Abstract to the page
+
<div class="pdbe-citations 1rgv" style="background-color:#fffaf0;"></div>
-
(as it appears on PubMed at http://www.pubmed.gov), where 14747735 is the PubMed ID number.
+
-
-->
+
-
{{ABSTRACT_PUBMED_14747735}}
+
-
 
+
-
==About this Structure==
+
-
[[1rgv]] is a 1 chain structure of [[Ferredoxin]] with sequence from [http://en.wikipedia.org/wiki/Thauera_aromatica_k172 Thauera aromatica k172]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RGV OCA].
+
==See Also==
==See Also==
-
*[[Ferredoxin]]
+
*[[Ferredoxin 3D structures|Ferredoxin 3D structures]]
-
 
+
== References ==
-
==Reference==
+
<references/>
-
<ref group="xtra">PMID:14747735</ref><references group="xtra"/>
+
__TOC__
-
[[Category: Thauera aromatica k172]]
+
</StructureSection>
-
[[Category: Boll, M.]]
+
[[Category: Large Structures]]
-
[[Category: Ermler, U.]]
+
[[Category: Thauera aromatica K172]]
-
[[Category: Unciuleac, M.]]
+
[[Category: Boll M]]
-
[[Category: Warkentin, E.]]
+
[[Category: Ermler U]]
-
[[Category: Electron transport]]
+
[[Category: Unciuleac M]]
 +
[[Category: Warkentin E]]

Current revision

Crystal Structure of the Ferredoxin from Thauera aromatica

PDB ID 1rgv

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1rgv"
Personal tools