2evu

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[[Image:2evu.png|left|200px]]
 
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==Crystal structure of aquaporin AqpM at 2.3A resolution==
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The line below this paragraph, containing "STRUCTURE_2evu", creates the "Structure Box" on the page.
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<StructureSection load='2evu' size='340' side='right'caption='[[2evu]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2evu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanothermobacter_marburgensis_str._Marburg Methanothermobacter marburgensis str. Marburg]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EVU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EVU FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BOG:B-OCTYLGLUCOSIDE'>BOG</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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{{STRUCTURE_2evu| PDB=2evu | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2evu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2evu OCA], [https://pdbe.org/2evu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2evu RCSB], [https://www.ebi.ac.uk/pdbsum/2evu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2evu ProSAT]</span></td></tr>
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</table>
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===Crystal structure of aquaporin AqpM at 2.3A resolution===
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== Function ==
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[https://www.uniprot.org/uniprot/AQPM_METTM AQPM_METTM] Channel that permits osmotically driven movement of water in both directions. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity. Exhibits also a transient but reproducible increase in the initial glycerol flux.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 16361443 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ev/2evu_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_16361443}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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[[2evu]] is a 1 chain structure of [[Aquaporin]] and [[Ion channels]] with sequence from [http://en.wikipedia.org/wiki/Methanothermobacter_marburgensis_str._marburg Methanothermobacter marburgensis str. marburg]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EVU OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2evu ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Aquaporin]]
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*[[Aquaporin 3D structures|Aquaporin 3D structures]]
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*[[Ion channels]]
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__TOC__
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</StructureSection>
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==Reference==
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[[Category: Large Structures]]
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<ref group="xtra">PMID:16361443</ref><references group="xtra"/>
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[[Category: Methanothermobacter marburgensis str. Marburg]]
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[[Category: Methanothermobacter marburgensis str. marburg]]
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[[Category: Agre P]]
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[[Category: Agre, P.]]
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[[Category: Kitagawa Y]]
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[[Category: CSMP, Center for Structures of Membrane Proteins.]]
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[[Category: Kozono D]]
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[[Category: Kitagawa, Y.]]
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[[Category: Lee JK]]
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[[Category: Kozono, D.]]
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[[Category: Remis J]]
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[[Category: Lee, J K.]]
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[[Category: Stroud RM]]
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[[Category: Remis, J.]]
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[[Category: Stroud, R M.]]
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[[Category: Alpha-helical]]
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[[Category: Center for structures of membrane protein]]
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[[Category: Csmp]]
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[[Category: Membrane protein]]
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[[Category: Protein structure initiative]]
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[[Category: Psi-2]]
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[[Category: Structural genomic]]
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Current revision

Crystal structure of aquaporin AqpM at 2.3A resolution

PDB ID 2evu

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