2ev1

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[[Image:2ev1.png|left|200px]]
 
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==Structure of Rv1264N, the regulatory domain of the mycobacterial adenylyl cylcase Rv1264, at pH 6.0==
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The line below this paragraph, containing "STRUCTURE_2ev1", creates the "Structure Box" on the page.
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<StructureSection load='2ev1' size='340' side='right'caption='[[2ev1]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2ev1]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EV1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EV1 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=OLA:OLEIC+ACID'>OLA</scene></td></tr>
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{{STRUCTURE_2ev1| PDB=2ev1 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ev1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ev1 OCA], [https://pdbe.org/2ev1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ev1 RCSB], [https://www.ebi.ac.uk/pdbsum/2ev1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ev1 ProSAT]</span></td></tr>
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</table>
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===Structure of Rv1264N, the regulatory domain of the mycobacterial adenylyl cylcase Rv1264, at pH 6.0===
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== Function ==
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[https://www.uniprot.org/uniprot/Y1264_MYCTU Y1264_MYCTU] Catalyzes the formation of the second messenger cAMP.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 17482646 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ev/2ev1_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_17482646}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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[[2ev1]] is a 2 chain structure of [[Adenylyl cyclase]] with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EV1 OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ev1 ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Adenylyl cyclase]]
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*[[3D Adenylyl cyclase 3D structures|3D Adenylyl cyclase 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:17482646</ref><references group="xtra"/>
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[[Category: Large Structures]]
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[[Category: Adenylate cyclase]]
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[[Category: Mycobacterium tuberculosis]]
[[Category: Mycobacterium tuberculosis]]
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[[Category: Findeisen, F.]]
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[[Category: Findeisen F]]
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[[Category: Sinning, I.]]
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[[Category: Sinning I]]
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[[Category: Tews, I.]]
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[[Category: Tews I]]
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[[Category: Alpha-helical]]
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[[Category: Lyase]]
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[[Category: Oleic acid]]
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[[Category: Regulatory domain of adenylyl cyclase]]
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Current revision

Structure of Rv1264N, the regulatory domain of the mycobacterial adenylyl cylcase Rv1264, at pH 6.0

PDB ID 2ev1

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