2zjt
From Proteopedia
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- | [[Image:2zjt.png|left|200px]] | ||
- | + | ==Crystal structure of dna gyrase B' domain sheds lights on the mechanism for T-segment navigation== | |
- | + | <StructureSection load='2zjt' size='340' side='right'caption='[[2zjt]], [[Resolution|resolution]] 2.80Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[2zjt]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZJT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZJT FirstGlance]. <br> | |
- | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8Å</td></tr> | |
- | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2zjt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zjt OCA], [https://pdbe.org/2zjt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2zjt RCSB], [https://www.ebi.ac.uk/pdbsum/2zjt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2zjt ProSAT]</span></td></tr> | |
- | + | </table> | |
- | + | == Function == | |
- | + | [https://www.uniprot.org/uniprot/GYRB_MYCTU GYRB_MYCTU] DNA gyrase negatively supercoils closed circular double-stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity). | |
- | + | == Evolutionary Conservation == | |
- | + | [[Image:Consurf_key_small.gif|200px|right]] | |
- | < | + | Check<jmol> |
- | + | <jmolCheckbox> | |
- | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zj/2zjt_consurf.spt"</scriptWhenChecked> | |
- | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |
- | + | <text>to colour the structure by Evolutionary Conservation</text> | |
- | + | </jmolCheckbox> | |
- | == | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2zjt ConSurf]. |
- | [[2zjt]] is a 2 chain structure | + | <div style="clear:both"></div> |
==See Also== | ==See Also== | ||
- | *[[Gyrase]] | + | *[[Gyrase 3D Structures|Gyrase 3D Structures]] |
- | + | __TOC__ | |
- | + | </StructureSection> | |
- | < | + | [[Category: Large Structures]] |
[[Category: Mycobacterium tuberculosis]] | [[Category: Mycobacterium tuberculosis]] | ||
- | [[Category: Fu | + | [[Category: Fu GS]] |
- | [[Category: Hu | + | [[Category: Hu YL]] |
- | [[Category: Wang | + | [[Category: Wang DC]] |
- | [[Category: Zhu | + | [[Category: Zhu DY]] |
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Current revision
Crystal structure of dna gyrase B' domain sheds lights on the mechanism for T-segment navigation
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