1r6b

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[[Image:1r6b.png|left|200px]]
 
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==High resolution crystal structure of ClpA==
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The line below this paragraph, containing "STRUCTURE_1r6b", creates the "Structure Box" on the page.
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<StructureSection load='1r6b' size='340' side='right'caption='[[1r6b]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1r6b]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R6B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1R6B FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.25&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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{{STRUCTURE_1r6b| PDB=1r6b | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1r6b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1r6b OCA], [https://pdbe.org/1r6b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1r6b RCSB], [https://www.ebi.ac.uk/pdbsum/1r6b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1r6b ProSAT]</span></td></tr>
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</table>
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===High resolution crystal structure of ClpA===
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== Function ==
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[https://www.uniprot.org/uniprot/CLPA_ECOLI CLPA_ECOLI] ATP-dependent specificity component of the ClpAP protease. It directs the protease to specific substrates. It has unfoldase activity. The primary function of the ClpA-ClpP complex appears to be the degradation of unfolded or abnormal proteins.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 15037248 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/r6/1r6b_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_15037248}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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[[1r6b]] is a 1 chain structure of [[Heat Shock Proteins]] with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R6B OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1r6b ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Heat Shock Proteins]]
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*[[Heat Shock Protein structures|Heat Shock Protein structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:15037248</ref><references group="xtra"/>
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Esser, L.]]
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[[Category: Large Structures]]
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[[Category: Guo, F.]]
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[[Category: Esser L]]
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[[Category: Maurizi, M R.]]
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[[Category: Guo F]]
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[[Category: Singh, S K.]]
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[[Category: Maurizi MR]]
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[[Category: Xia, D.]]
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[[Category: Singh SK]]
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[[Category: Aaa+]]
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[[Category: Xia D]]
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[[Category: Binding mechanism]]
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[[Category: Clpa]]
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[[Category: Clp]]
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[[Category: Crystal]]
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[[Category: Hydrolase]]
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[[Category: N-terminal domain]]
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Current revision

High resolution crystal structure of ClpA

PDB ID 1r6b

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