1ih5

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[[Image:1ih5.png|left|200px]]
 
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==CRYSTAL STRUCTURE OF AQUAPORIN-1==
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The line below this paragraph, containing "STRUCTURE_1ih5", creates the "Structure Box" on the page.
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<StructureSection load='1ih5' size='340' side='right'caption='[[1ih5]], [[Resolution|resolution]] 3.70&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1ih5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1hw0 1hw0]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IH5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1IH5 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron crystallography, [[Resolution|Resolution]] 3.7&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ih5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ih5 OCA], [https://pdbe.org/1ih5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ih5 RCSB], [https://www.ebi.ac.uk/pdbsum/1ih5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ih5 ProSAT]</span></td></tr>
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{{STRUCTURE_1ih5| PDB=1ih5 | SCENE= }}
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</table>
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== Function ==
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===CRYSTAL STRUCTURE OF AQUAPORIN-1===
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[https://www.uniprot.org/uniprot/AQP1_HUMAN AQP1_HUMAN] Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient.<ref>PMID:1373524</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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(as it appears on PubMed at http://www.pubmed.gov), where 11171962 is the PubMed ID number.
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ih/1ih5_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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{{ABSTRACT_PUBMED_11171962}}
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==About this Structure==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ih5 ConSurf].
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[[1ih5]] is a 1 chain structure of [[Aquaporin]] and [[Ion channels]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1hw0 1hw0]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IH5 OCA].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Aquaporin]]
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*[[Aquaporin 3D structures|Aquaporin 3D structures]]
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*[[Ion channels]]
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== References ==
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<references/>
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==Reference==
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__TOC__
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<ref group="xtra">PMID:11171962</ref><references group="xtra"/>
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Cheng, A.]]
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[[Category: Large Structures]]
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[[Category: Melnyk, P.]]
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[[Category: Cheng A]]
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[[Category: Mitra, A K.]]
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[[Category: Melnyk P]]
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[[Category: Reddy, V S.]]
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[[Category: Mitra AK]]
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[[Category: Ren, G.]]
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[[Category: Reddy VS]]
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[[Category: Electron microscopy]]
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[[Category: Ren G]]
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[[Category: Membrane protein]]
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[[Category: Two-dimensional crystal]]
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[[Category: Water channel]]
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Current revision

CRYSTAL STRUCTURE OF AQUAPORIN-1

PDB ID 1ih5

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