1jr9

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[[Image:1jr9.png|left|200px]]
 
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==Crystal Structure of manganese superoxide dismutases from Bacillus halodenitrificans==
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The line below this paragraph, containing "STRUCTURE_1jr9", creates the "Structure Box" on the page.
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<StructureSection load='1jr9' size='340' side='right'caption='[[1jr9]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1jr9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Virgibacillus_halodenitrificans Virgibacillus halodenitrificans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JR9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JR9 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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{{STRUCTURE_1jr9| PDB=1jr9 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1jr9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jr9 OCA], [https://pdbe.org/1jr9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1jr9 RCSB], [https://www.ebi.ac.uk/pdbsum/1jr9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1jr9 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/SODM_VIRHA SODM_VIRHA] Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems. Active only in homodimeric state.<ref>PMID:12457847</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jr/1jr9_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1jr9 ConSurf].
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<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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A so-called "green protein" has been purified from a moderate halophilic eubacterium, Bacillus halodenitrificans (ATCC 49067), under anaerobic conditions. The protein, which might play an important role in denitrification, dissociates mainly into two components after exposure to air: a manganese superoxide dismutase (GP-MnSOD) and a nucleoside diphosphate kinase. As a first step in elucidating the overall structure of the green protein and the role of each component, the 2.8-A resolution crystal structure of GP-MnSOD was determined. Compared with other manganese dismutases, GP-MnSOD shows two significant characteristics. The first is that the entrance to its substrate channel has an additional basic residue-Lys38. The second is that its surface is decorated with an excess of acidic over basic residues. All these structural features may be related to GP-MnSOD's high catalytic activity and its endurance against the special cytoplasm of B. halodenitrificans. The structure of GP-MnSOD provides the basis for recognizing its possible role and assembly state in the green protein.
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===Crystal Structure of manganese superoxide dismutases from Bacillus halodenitrificans===
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Three-dimensional structure of manganese superoxide dismutase from Bacillus halodenitrificans, a component of the so-called "green protein".,Liao J, Liu MY, Chang T, Li M, Le Gall J, Gui LL, Zhang JP, Jiang T, Liang DC, Chang WR J Struct Biol. 2002 Sep;139(3):171-80. PMID:12457847<ref>PMID:12457847</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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<div class="pdbe-citations 1jr9" style="background-color:#fffaf0;"></div>
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(as it appears on PubMed at http://www.pubmed.gov), where 12457847 is the PubMed ID number.
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{{ABSTRACT_PUBMED_12457847}}
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==About this Structure==
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[[1jr9]] is a 1 chain structure of [[Superoxide Dismutase]] with sequence from [http://en.wikipedia.org/wiki/Virgibacillus_halodenitrificans Virgibacillus halodenitrificans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JR9 OCA].
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==See Also==
==See Also==
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*[[Superoxide Dismutase]]
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*[[Superoxide dismutase 3D structures|Superoxide dismutase 3D structures]]
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:12457847</ref><references group="xtra"/>
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__TOC__
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[[Category: Superoxide dismutase]]
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Virgibacillus halodenitrificans]]
[[Category: Virgibacillus halodenitrificans]]
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[[Category: Chang, T.]]
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[[Category: Chang T]]
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[[Category: Chang, W R.]]
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[[Category: Chang WR]]
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[[Category: Gui, L L.]]
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[[Category: Gui LL]]
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[[Category: Jiang, T.]]
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[[Category: Jiang T]]
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[[Category: LeGall, J.]]
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[[Category: LeGall J]]
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[[Category: Li, M.]]
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[[Category: Li M]]
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[[Category: Liang, D C.]]
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[[Category: Liang DC]]
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[[Category: Liao, J.]]
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[[Category: Liao J]]
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[[Category: Liu, M Y.]]
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[[Category: Liu MY]]
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[[Category: Zhang, J P.]]
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[[Category: Zhang JP]]
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[[Category: Manganese superoxide dismutase]]
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[[Category: Oxidoreductase]]
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Current revision

Crystal Structure of manganese superoxide dismutases from Bacillus halodenitrificans

PDB ID 1jr9

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