This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1r4z

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (06:12, 3 April 2024) (edit) (undo)
 
(9 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:1r4z.png|left|200px]]
 
-
<!--
+
==Bacillus subtilis lipase A with covalently bound Rc-IPG-phosphonate-inhibitor==
-
The line below this paragraph, containing "STRUCTURE_1r4z", creates the "Structure Box" on the page.
+
<StructureSection load='1r4z' size='340' side='right'caption='[[1r4z]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[1r4z]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R4Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1R4Z FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=RIL:[(4R)-2,2-DIMETHYL-1,3-DIOXOLAN-4-YL]METHYL+HYDROGEN+HEX-5-ENYLPHOSPHONATE'>RIL</scene></td></tr>
-
{{STRUCTURE_1r4z| PDB=1r4z | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1r4z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1r4z OCA], [https://pdbe.org/1r4z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1r4z RCSB], [https://www.ebi.ac.uk/pdbsum/1r4z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1r4z ProSAT]</span></td></tr>
-
 
+
</table>
-
===Bacillus subtilis lipase A with covalently bound Rc-IPG-phosphonate-inhibitor===
+
== Function ==
-
 
+
[https://www.uniprot.org/uniprot/ESTA_BACSU ESTA_BACSU] Active toward p-nitrophenyl esters and triacylglycerides with a marked preference for esters with C8 acyl groups.<ref>PMID:8396026</ref>
-
 
+
== Evolutionary Conservation ==
-
<!--
+
[[Image:Consurf_key_small.gif|200px|right]]
-
The line below this paragraph, {{ABSTRACT_PUBMED_16342303}}, adds the Publication Abstract to the page
+
Check<jmol>
-
(as it appears on PubMed at http://www.pubmed.gov), where 16342303 is the PubMed ID number.
+
<jmolCheckbox>
-
-->
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/r4/1r4z_consurf.spt"</scriptWhenChecked>
-
{{ABSTRACT_PUBMED_16342303}}
+
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-
 
+
<text>to colour the structure by Evolutionary Conservation</text>
-
==About this Structure==
+
</jmolCheckbox>
-
[[1r4z]] is a 2 chain structure of [[Lipase]] with sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R4Z OCA].
+
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1r4z ConSurf].
 +
<div style="clear:both"></div>
==See Also==
==See Also==
-
*[[Lipase]]
+
*[[Lipase 3D Structures|Lipase 3D Structures]]
-
 
+
== References ==
-
==Reference==
+
<references/>
-
<ref group="xtra">PMID:16342303</ref><references group="xtra"/>
+
__TOC__
 +
</StructureSection>
[[Category: Bacillus subtilis]]
[[Category: Bacillus subtilis]]
-
[[Category: Triacylglycerol lipase]]
+
[[Category: Large Structures]]
-
[[Category: Dijkstra, B W.]]
+
[[Category: Dijkstra BW]]
-
[[Category: Droege, M J.]]
+
[[Category: Droege MJ]]
-
[[Category: Pouderoyen, G Van.]]
+
[[Category: Quax WJ]]
-
[[Category: Quax, W J.]]
+
[[Category: Reetz MT]]
-
[[Category: Reetz, M T.]]
+
[[Category: Rueggeberg CJ]]
-
[[Category: Rueggeberg, C J.]]
+
[[Category: Van Pouderoyen G]]
-
[[Category: Vrenken, T E.]]
+
[[Category: Vrenken TE]]
-
[[Category: Alpha/beta hydrolase]]
+
-
[[Category: Lipase]]
+
-
[[Category: Phosphonate inhibitor]]
+

Current revision

Bacillus subtilis lipase A with covalently bound Rc-IPG-phosphonate-inhibitor

PDB ID 1r4z

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1r4z"
Personal tools