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2iii
From Proteopedia
(Difference between revisions)
(New page: 200px<br /><applet load="2iii" size="350" color="white" frame="true" align="right" spinBox="true" caption="2iii, resolution 2.30Å" /> '''Crystal structure of...) |
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| - | [[Image:2iii.gif|left|200px]]<br /><applet load="2iii" size="350" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="2iii, resolution 2.30Å" /> | ||
| - | '''Crystal structure of the adenosylmethionine decarboxylase (aq_254) from aquifex aeolicus vf5'''<br /> | ||
| - | == | + | ==Crystal structure of the adenosylmethionine decarboxylase (aq_254) from aquifex aeolicus vf5== |
| - | + | <StructureSection load='2iii' size='340' side='right'caption='[[2iii]], [[Resolution|resolution]] 2.30Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2iii]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Aquifex_aeolicus_VF5 Aquifex aeolicus VF5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2III OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2III FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3Å</td></tr> | |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | |
| - | [ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2iii FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iii OCA], [https://pdbe.org/2iii PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2iii RCSB], [https://www.ebi.ac.uk/pdbsum/2iii PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2iii ProSAT], [https://www.topsan.org/Proteins/RSGI/2iii TOPSAN]</span></td></tr> |
| - | + | </table> | |
| - | [ | + | == Function == |
| - | + | [https://www.uniprot.org/uniprot/SPEH_AQUAE SPEH_AQUAE] Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity). | |
| - | + | == Evolutionary Conservation == | |
| - | [ | + | [[Image:Consurf_key_small.gif|200px|right]] |
| - | + | Check<jmol> | |
| - | [ | + | <jmolCheckbox> |
| - | [ | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ii/2iii_consurf.spt"</scriptWhenChecked> |
| - | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |
| - | + | <text>to colour the structure by Evolutionary Conservation</text> | |
| - | [[ | + | </jmolCheckbox> |
| - | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2iii ConSurf]. | |
| - | + | <div style="clear:both"></div> | |
| - | + | ||
| - | [ | + | |
| - | [[ | + | |
| - | [ | + | |
| - | + | ||
| - | + | ==See Also== | |
| + | *[[SAM decarboxylase|SAM decarboxylase]] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Aquifex aeolicus VF5]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Baba S]] | ||
| + | [[Category: Ebihara A]] | ||
| + | [[Category: Jeyakanthan J]] | ||
| + | [[Category: Kanaujia SP]] | ||
| + | [[Category: Kuramitsu S]] | ||
| + | [[Category: Sekar K]] | ||
| + | [[Category: Shinkai A]] | ||
| + | [[Category: Shiro Y]] | ||
| + | [[Category: Vasuki Ranjani C]] | ||
| + | [[Category: Yokoyama S]] | ||
Current revision
Crystal structure of the adenosylmethionine decarboxylase (aq_254) from aquifex aeolicus vf5
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