This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2b6p

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "2b6p" [edit=sysop:move=sysop])
Current revision (09:16, 14 February 2024) (edit) (undo)
 
(9 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:2b6p.png|left|200px]]
 
-
<!--
+
==X-ray structure of lens Aquaporin-0 (AQP0) (lens MIP) in an open pore state==
-
The line below this paragraph, containing "STRUCTURE_2b6p", creates the "Structure Box" on the page.
+
<StructureSection load='2b6p' size='340' side='right'caption='[[2b6p]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[2b6p]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B6P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2B6P FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
-
-->
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2b6p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b6p OCA], [https://pdbe.org/2b6p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2b6p RCSB], [https://www.ebi.ac.uk/pdbsum/2b6p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2b6p ProSAT]</span></td></tr>
-
{{STRUCTURE_2b6p| PDB=2b6p | SCENE= }}
+
</table>
-
 
+
== Function ==
-
===X-ray structure of lens Aquaporin-0 (AQP0) (lens MIP) in an open pore state===
+
[https://www.uniprot.org/uniprot/MIP_BOVIN MIP_BOVIN] Water channel. May be responsible for regulating the osmolarity of the lens. Interactions between homotetramers from adjoining membranes may stabilize cell junctions in the eye lens core.<ref>PMID:16319884</ref>
-
 
+
== Evolutionary Conservation ==
-
 
+
[[Image:Consurf_key_small.gif|200px|right]]
-
<!--
+
Check<jmol>
-
The line below this paragraph, {{ABSTRACT_PUBMED_16319884}}, adds the Publication Abstract to the page
+
<jmolCheckbox>
-
(as it appears on PubMed at http://www.pubmed.gov), where 16319884 is the PubMed ID number.
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b6/2b6p_consurf.spt"</scriptWhenChecked>
-
-->
+
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-
{{ABSTRACT_PUBMED_16319884}}
+
<text>to colour the structure by Evolutionary Conservation</text>
-
 
+
</jmolCheckbox>
-
==About this Structure==
+
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2b6p ConSurf].
-
[[2b6p]] is a 1 chain structure of [[Ion channels]] with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B6P OCA].
+
<div style="clear:both"></div>
==See Also==
==See Also==
-
*[[Ion channels]]
+
*[[Aquaporin 3D structures|Aquaporin 3D structures]]
-
 
+
== References ==
-
==Reference==
+
<references/>
-
<ref group="xtra">PMID:16319884</ref><ref group="xtra">PMID:15377788</ref><references group="xtra"/>
+
__TOC__
 +
</StructureSection>
[[Category: Bos taurus]]
[[Category: Bos taurus]]
-
[[Category: Cheng, Y.]]
+
[[Category: Large Structures]]
-
[[Category: Fujiyoshi, Y.]]
+
[[Category: Cheng Y]]
-
[[Category: Gonen, T.]]
+
[[Category: Fujiyoshi Y]]
-
[[Category: Harrison, S C.]]
+
[[Category: Gonen T]]
-
[[Category: Hiroaki, Y.]]
+
[[Category: Harrison SC]]
-
[[Category: Sliz, P.]]
+
[[Category: Hiroaki Y]]
-
[[Category: Walz, T.]]
+
[[Category: Sliz P]]
-
[[Category: Aqp0]]
+
[[Category: Walz T]]
-
[[Category: Aquaporin]]
+
-
[[Category: Aquaporin-0]]
+
-
[[Category: Lens mip]]
+
-
[[Category: Membrane protein]]
+
-
[[Category: Open water pore]]
+

Current revision

X-ray structure of lens Aquaporin-0 (AQP0) (lens MIP) in an open pore state

PDB ID 2b6p

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2b6p"
Personal tools