Template:STRUCTURE 2hyy
From Proteopedia
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{{Structure | {{Structure | ||
|PDB= {{{PDB}}}|SCENE={{{SCENE|}}}|SIZE={{{SIZE|350}}}|CAPTION={{{CAPTION|[[2hyy]], [[Resolution|resolution]] 2.40Å (<scene name='initialview01'>default scene</scene>)}}} | |PDB= {{{PDB}}}|SCENE={{{SCENE|}}}|SIZE={{{SIZE|350}}}|CAPTION={{{CAPTION|[[2hyy]], [[Resolution|resolution]] 2.40Å (<scene name='initialview01'>default scene</scene>)}}} | ||
| - | |SITE= <scene name='pdbsite=AC1:Binding+Site+For+Residue+Sti+A+600'>AC1</scene>, <scene name='pdbsite=AC2:Binding+Site+For+Residue+Sti+B+600'>AC2</scene>, <scene name='pdbsite=AC3:Binding+Site+For+Residue+Sti+C+600'>AC3</scene> and <scene name='pdbsite=AC4:Binding+Site+For+Residue+Sti+D+600'>AC4</scene> | ||
|LIGAND= <scene name='pdbligand=STI:4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL]-BENZAMIDE'>STI</scene> | |LIGAND= <scene name='pdbligand=STI:4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL]-BENZAMIDE'>STI</scene> | ||
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_protein-tyrosine_kinase Non-specific protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.2 2.7.10.2] </span> | |ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_protein-tyrosine_kinase Non-specific protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.2 2.7.10.2] </span> | ||
|GENE= ABL1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]) | |GENE= ABL1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]) | ||
|RELATEDENTRY=[[1iep|1iep]], [[1fpu|1fpu]] | |RELATEDENTRY=[[1iep|1iep]], [[1fpu|1fpu]] | ||
| - | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2hyy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hyy OCA], [http://www. | + | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2hyy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hyy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2hyy RCSB], [http://www.ebi.ac.uk/pdbsum/2hyy PDBsum]</span> |
|FUNCTION={{GO|id=GO:0005524 | text = ATP binding}}{{GO|id=GO:0016740 | text = transferase activity}}{{GO|id=GO:0004713 | text = protein-tyrosine kinase activity}}{{GO|id=GO:0008022 | text = protein C-terminus binding}}{{GO|id=GO:0000166 | text = nucleotide binding}}{{GO|id=GO:0030145 | text = manganese ion binding}}{{GO|id=GO:0000287 | text = magnesium ion binding}}{{GO|id=GO:0004672 | text = protein kinase activity}}{{GO|id=GO:0016301 | text = kinase activity}}{{GO|id=GO:0005515 | text = protein binding}}{{GO|id=GO:0003677 | text = DNA binding}}{{GO|id=GO:0046872 | text = metal ion binding}} | |FUNCTION={{GO|id=GO:0005524 | text = ATP binding}}{{GO|id=GO:0016740 | text = transferase activity}}{{GO|id=GO:0004713 | text = protein-tyrosine kinase activity}}{{GO|id=GO:0008022 | text = protein C-terminus binding}}{{GO|id=GO:0000166 | text = nucleotide binding}}{{GO|id=GO:0030145 | text = manganese ion binding}}{{GO|id=GO:0000287 | text = magnesium ion binding}}{{GO|id=GO:0004672 | text = protein kinase activity}}{{GO|id=GO:0016301 | text = kinase activity}}{{GO|id=GO:0005515 | text = protein binding}}{{GO|id=GO:0003677 | text = DNA binding}}{{GO|id=GO:0046872 | text = metal ion binding}} | ||
|PROCESS={{GO|id=GO:0030036 | text = actin cytoskeleton organization and biogenesis}}{{GO|id=GO:0006468 | text = protein amino acid phosphorylation}}{{GO|id=GO:0018108 | text = peptidyl-tyrosine phosphorylation}}{{GO|id=GO:0007242 | text = intracellular signaling cascade}}{{GO|id=GO:0006298 | text = mismatch repair}}{{GO|id=GO:0008630 | text = DNA damage response, signal transduction resulting in induction of apoptosis}}{{GO|id=GO:0000115 | text = S-phase-specific transcription in mitotic cell cycle}}{{GO|id=GO:0006355 | text = regulation of transcription, DNA-dependent}}{{GO|id=GO:0007155 | text = cell adhesion}}{{GO|id=GO:0006464 | text = protein modification process}} | |PROCESS={{GO|id=GO:0030036 | text = actin cytoskeleton organization and biogenesis}}{{GO|id=GO:0006468 | text = protein amino acid phosphorylation}}{{GO|id=GO:0018108 | text = peptidyl-tyrosine phosphorylation}}{{GO|id=GO:0007242 | text = intracellular signaling cascade}}{{GO|id=GO:0006298 | text = mismatch repair}}{{GO|id=GO:0008630 | text = DNA damage response, signal transduction resulting in induction of apoptosis}}{{GO|id=GO:0000115 | text = S-phase-specific transcription in mitotic cell cycle}}{{GO|id=GO:0006355 | text = regulation of transcription, DNA-dependent}}{{GO|id=GO:0007155 | text = cell adhesion}}{{GO|id=GO:0006464 | text = protein modification process}} | ||
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