3q2s

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'''Unreleased structure'''
 
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The entry 3q2s is ON HOLD
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==Crystal Structure of CFIm68 RRM/CFIm25 complex==
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<StructureSection load='3q2s' size='340' side='right'caption='[[3q2s]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
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Authors: Yang, Q.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3q2s]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q2S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3Q2S FirstGlance]. <br>
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Description: Crystal Stucture of Nudt21
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3q2s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q2s OCA], [https://pdbe.org/3q2s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3q2s RCSB], [https://www.ebi.ac.uk/pdbsum/3q2s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3q2s ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CPSF5_HUMAN CPSF5_HUMAN] Component of the cleavage factor Im (CFIm) complex that plays a key role in pre-mRNA 3'-processing. Involved in association with CPSF6 or CPSF7 in pre-MRNA 3'-end poly(A) site cleavage and poly(A) addition. NUDT21/CPSF5 binds to cleavage and polyadenylation RNA substrates. The homodimer mediates simultaneous sequence-specific recognition of two 5'-UGUA-3' elements within the pre-mRNA. Binds to, but does not hydrolyze mono- and di-adenosine nucleotides. May have a role in mRNA export.<ref>PMID:9659921</ref> <ref>PMID:8626397</ref> <ref>PMID:14690600</ref> <ref>PMID:20695905</ref> <ref>PMID:20479262</ref> <ref>PMID:21295486</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Coseno M]]
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[[Category: Doublie S]]
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[[Category: Gilmartin GM]]
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[[Category: Yang Q]]

Current revision

Crystal Structure of CFIm68 RRM/CFIm25 complex

PDB ID 3q2s

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