3p5p

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[[Image:3p5p.jpg|left|200px]]
 
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==Crystal Structure of Taxadiene Synthase from Pacific Yew (Taxus brevifolia) in complex with Mg2+ and 13-aza-13,14-dihydrocopalyl diphosphate==
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The line below this paragraph, containing "STRUCTURE_3p5p", creates the "Structure Box" on the page.
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<StructureSection load='3p5p' size='340' side='right'caption='[[3p5p]], [[Resolution|resolution]] 1.82&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3p5p]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Taxus_brevifolia Taxus brevifolia]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P5P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3P5P FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.816&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A3C:2-(METHYL{2-[(1S,4AS,8AS)-5,5,8A-TRIMETHYL-2-METHYLIDENEDECAHYDRONAPHTHALEN-1-YL]ETHYL}AMINO)ETHYL+TRIHYDROGEN+DIPHOSPHATE'>A3C</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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{{STRUCTURE_3p5p| PDB=3p5p | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3p5p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3p5p OCA], [https://pdbe.org/3p5p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3p5p RCSB], [https://www.ebi.ac.uk/pdbsum/3p5p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3p5p ProSAT]</span></td></tr>
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</table>
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===Crystal Structure of Taxadiene Synthase from Pacific Yew (Taxus brevifolia) in complex with Mg2+ and 13-aza-13,14-dihydrocopalyl diphosphate===
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== Function ==
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[https://www.uniprot.org/uniprot/TASY_TAXBR TASY_TAXBR] Catalyzes the cyclization of the ubiquitous isoprenoid intermediate geranylgeranyl diphosphate to taxa-4,11-diene, the parent olefin with a taxane skeleton.
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_21160477}}, adds the Publication Abstract to the page
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[[Category: Large Structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 21160477 is the PubMed ID number.
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{{ABSTRACT_PUBMED_21160477}}
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==About this Structure==
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[[3p5p]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Taxus_brevifolia Taxus brevifolia]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P5P OCA].
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==Reference==
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<ref group="xtra">PMID:21160477</ref><references group="xtra"/>
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[[Category: Taxadiene synthase]]
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[[Category: Taxus brevifolia]]
[[Category: Taxus brevifolia]]
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[[Category: Christianson, D W.]]
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[[Category: Christianson DW]]
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[[Category: Koksal, M.]]
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[[Category: Koksal M]]
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[[Category: 3-azacopalyl diphosphate]]
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[[Category: Biosynthesis of paclitaxel]]
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[[Category: Class i and ii terpene cyclase fold]]
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[[Category: Ddxxd motif]]
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[[Category: Diterpene cyclase]]
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[[Category: Lyase]]
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[[Category: Nse/dte motif]]
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Current revision

Crystal Structure of Taxadiene Synthase from Pacific Yew (Taxus brevifolia) in complex with Mg2+ and 13-aza-13,14-dihydrocopalyl diphosphate

PDB ID 3p5p

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