3ahp

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[[Image:3ahp.jpg|left|200px]]
 
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==Crystal structure of stable protein, CutA1, from a psychrotrophic bacterium Shewanella sp. SIB1==
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The line below this paragraph, containing "STRUCTURE_3ahp", creates the "Structure Box" on the page.
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<StructureSection load='3ahp' size='340' side='right'caption='[[3ahp]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3ahp]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Shewanella_sp._SIB1 Shewanella sp. SIB1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AHP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3AHP FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ahp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ahp OCA], [https://pdbe.org/3ahp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ahp RCSB], [https://www.ebi.ac.uk/pdbsum/3ahp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ahp ProSAT]</span></td></tr>
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{{STRUCTURE_3ahp| PDB=3ahp | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/E7FH74_9GAMM E7FH74_9GAMM]
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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CutA1 is widely found in bacteria, plants and animals, including humans. The functions of CutA1, however, have not been well clarified. It is known that CutA1s from Pyrococcus horikoshii, Thermus thermophilus and Oryza sativa unfold at temperatures remarkably higher than the growth temperatures of the host organisms. In this work the crystal structure of CutA1 from the psychrotrophic bacterium Shewanella sp. SIB1 (SIB1-CutA1) in a trimeric form was determined at 2.7 A resolution. This is the first crystal structure of a psychrotrophic CutA1. The overall structure of SIB1-CutA1 is similar to those of CutA1 from Homo sapiens, Escherichia coli, Pyrococcus horikoshii, Thermus thermophilus, Termotoga maritima, Oryza sativa and Rattus norvergicus. A peculiarity is observed in the beta2 strand. The beta2 strand is divided into two short beta strands, beta2a and beta2b, in SIB1-CutA1. A thermal denaturation experiment revealed that SIB1-CutA1 does not unfold completely at 363 K at pH 7.0, although Shewanella sp. SIB1 cannot grow at temperatures exceeding 303 K. These results indicate that the trimeric structural motif of CutA1 is the critical factor in its unusually high stability and suggest that CutA1 needs to maintain its high stability in order to function, even in psychrotrophs.
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===Crystal structure of stable protein, CutA1, from a psychrotrophic bacterium Shewanella sp. SIB1===
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Crystal structure of stable protein CutA1 from psychrotrophic bacterium Shewanella sp. SIB1.,Sato A, Yokotani S, Tadokoro T, Tanaka SI, Angkawidjaja C, Koga Y, Takano K, Kanaya S J Synchrotron Radiat. 2011 Jan;18(1):6-10. Epub 2010 Nov 12. PMID:21169681<ref>PMID:21169681</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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<div class="pdbe-citations 3ahp" style="background-color:#fffaf0;"></div>
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==See Also==
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The line below this paragraph, {{ABSTRACT_PUBMED_21169681}}, adds the Publication Abstract to the page
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*[[CutA1 3D structures|CutA1 3D structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 21169681 is the PubMed ID number.
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== References ==
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<references/>
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{{ABSTRACT_PUBMED_21169681}}
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__TOC__
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</StructureSection>
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==About this Structure==
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[[Category: Large Structures]]
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[[3ahp]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Shewanella Shewanella]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AHP OCA].
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[[Category: Shewanella sp. SIB1]]
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[[Category: Angkawidjaja C]]
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==Reference==
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[[Category: Kanaya S]]
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<ref group="xtra">PMID:21169681</ref><references group="xtra"/>
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[[Category: Koga Y]]
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[[Category: Shewanella]]
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[[Category: Takano K]]
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[[Category: Angkawidjaja, C.]]
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[[Category: Tanaka S]]
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[[Category: Kanaya, S.]]
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[[Category: Koga, Y.]]
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[[Category: Takano, K.]]
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[[Category: Tanaka, S.]]
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Current revision

Crystal structure of stable protein, CutA1, from a psychrotrophic bacterium Shewanella sp. SIB1

PDB ID 3ahp

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