6cro

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[[Image:6cro.png|left|200px]]
 
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==CRYSTAL STRUCTURE OF LAMBDA-CRO BOUND TO A CONSENSUS OPERATOR AT 3.0 ANGSTROM RESOLUTION==
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The line below this paragraph, containing "STRUCTURE_6cro", creates the "Structure Box" on the page.
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<StructureSection load='6cro' size='340' side='right'caption='[[6cro]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[6cro]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_Lambda Escherichia virus Lambda]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CRO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6CRO FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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{{STRUCTURE_6cro| PDB=6cro | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6cro FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6cro OCA], [https://pdbe.org/6cro PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6cro RCSB], [https://www.ebi.ac.uk/pdbsum/6cro PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6cro ProSAT]</span></td></tr>
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</table>
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===CRYSTAL STRUCTURE OF LAMBDA-CRO BOUND TO A CONSENSUS OPERATOR AT 3.0 ANGSTROM RESOLUTION===
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== Function ==
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[https://www.uniprot.org/uniprot/RCRO_LAMBD RCRO_LAMBD] Cro represses genes normally expressed in early phage development and is necessary for the late stage of lytic growth. It does this by binding to the OL and OR operators regions normally used by the repressor protein for lysogenic maintenance.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 9653037 is the PubMed ID number.
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cr/6cro_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_9653037}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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[[6cro]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_lambda Enterobacteria phage lambda]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CRO OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=6cro ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Tomato aspermy virus protein 2b Suppression of RNA Silencing]]
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*[[Tomato aspermy virus protein 2b Suppression of RNA Silencing|Tomato aspermy virus protein 2b Suppression of RNA Silencing]]
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*[[User:Wayne Decatur/Tomato aspermy virus protein 2b Suppression of RNA Silencing]]
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__TOC__
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</StructureSection>
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==Reference==
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[[Category: Escherichia virus Lambda]]
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<ref group="xtra">PMID:9653037</ref><references group="xtra"/>
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[[Category: Large Structures]]
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[[Category: Enterobacteria phage lambda]]
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[[Category: Albright RA]]
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[[Category: Albright, R A.]]
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[[Category: Matthews BW]]
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[[Category: Matthews, B W.]]
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[[Category: Bacteriophage lambda]]
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[[Category: Conformational change]]
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[[Category: Cro]]
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[[Category: Gene regulation/dna complex]]
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[[Category: Helix-turn-helix]]
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[[Category: Repressor]]
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Current revision

CRYSTAL STRUCTURE OF LAMBDA-CRO BOUND TO A CONSENSUS OPERATOR AT 3.0 ANGSTROM RESOLUTION

PDB ID 6cro

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