3pkp
From Proteopedia
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| - | [[Image:3pkp.jpg|left|200px]] | ||
| - | < | + | ==Q83S Variant of S. Enterica RmlA with dATP== |
| - | + | <StructureSection load='3pkp' size='340' side='right'caption='[[3pkp]], [[Resolution|resolution]] 2.60Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3pkp]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium Salmonella enterica subsp. enterica serovar Typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PKP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PKP FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6Å</td></tr> | |
| - | --> | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DTP:2-DEOXYADENOSINE+5-TRIPHOSPHATE'>DTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3pkp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pkp OCA], [https://pdbe.org/3pkp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3pkp RCSB], [https://www.ebi.ac.uk/pdbsum/3pkp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3pkp ProSAT]</span></td></tr> | |
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/RMLA_SALTY RMLA_SALTY] Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Is also able to convert non natural substrates such as a wide array of alpha-D-hexopyranosyl, deoxy-alpha-D-glucopyranosyl, aminodeoxy-alpha-D-hexopyranosyl and acetamidodeoxy-alpha-D-hexopyranosyl phosphates to their corresponding dTDP- and UDP-nucleotide sugars.<ref>PMID:8382158</ref> | ||
| - | == | + | ==See Also== |
| - | + | *[[Glucose-1-phosphate thymidylyltransferase 3D structures|Glucose-1-phosphate thymidylyltransferase 3D structures]] | |
| - | + | == References == | |
| - | == | + | <references/> |
| - | + | __TOC__ | |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: Salmonella enterica subsp. enterica serovar | + | [[Category: Large Structures]] |
| - | [[Category: Bingman | + | [[Category: Salmonella enterica subsp. enterica serovar Typhimurium]] |
| - | + | [[Category: Bingman CA]] | |
| - | [[Category: Chang | + | [[Category: Chang A]] |
| - | [[Category: Moretti | + | [[Category: Moretti R]] |
| - | [[Category: Phillips | + | [[Category: Phillips Jr GN]] |
| - | [[Category: Thorson | + | [[Category: Thorson JS]] |
Current revision
Q83S Variant of S. Enterica RmlA with dATP
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